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ABE608

Sigma-Aldrich

Anti-APC10 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Anaphase promoting complex 10, Cyclosome subunit 10, APC10

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

human (immunogen homology)

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ANAPC10(10393)

General description

Anaphase-promoting complex subunit 10 (APC10) is a component of the anaphase promoting complex/cyclosome (APC/C) which mediates the ubiquitination and subsequent degradation of target proteins. The individual mRNA and protein levels of the APC/C are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.

Immunogen

KLH-conjugated linear peptide corresponding to human APC10.

Application

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected APC10 in mouse heart tissue.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair
This Anti-APC10 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of APC10.

Quality

Evaluated by Western Blotting in mouse heart tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected APC10 in 15 µg of mouse heart tissue lysate.

Target description

~21 kDa observed

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse heart tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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