ABN475

Anti-Wnt Antibody-10b

from rabbit, purified by affinity chromatography

• Synonym(s): Protein Wnt-10b, Protein Wnt-12
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• technique(s): immunohistochemistry: suitable; western blot: suitable
• UniProt accession no.: O00744
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... WNT10B(7480)

Description

General description

Protein Wnt-10b (Wnt-10b) is a member of the Wnt family that plays an important role in normal development such as regulation of cell fate, patterning during embryogenesis, and neoplastic transformation. Wnt-10b may promote epithelial cell differentiation and hair shaft growth, demonstrating that Wnt-10b has multiple roles in cell growth and differentiation. Mutations in Wnt-10b have been associated with an autosomal receesive disorder known as split-hand/foot malformation type 6 (SHFM6).

Immunogen

KLH-conjugated linear peptide corresponding to human Wnt-10b.

Application

Detect Wnt using this rabbit polyclonal antibody, Anti-Wnt Antibody-10b validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected Wnt-10b in human skeletal muscle tissue.

Quality

Evaluated by Western Blotting in human skeletal muscle tissue lysate.

Western Blotting Analysis: 4 µg/mL of this antibody detected Wnt-10b in 15 µg of human skeletal muscle tissue lysate.

Target description

~45 kDa observed. Uncharacterized bands may appear in some lysates.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable