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AP160P

Sigma-Aldrich

Rabbit Anti-Mouse IgG Antibody, HRP conjugate

Chemicon®, from rabbit

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eCl@ss:
32160702
NACRES:
NA.46

biological source

rabbit

Quality Level

conjugate

peroxidase conjugate

antibody form

F(ab′)2 fragment of affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

shipped in

wet ice

target post-translational modification

unmodified

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AQ160PAP130PAP108P
biological source

rabbit

biological source

rabbit

biological source

goat

biological source

goat

conjugate

peroxidase conjugate

conjugate

peroxidase conjugate

conjugate

peroxidase conjugate

conjugate

peroxidase conjugate

technique(s)

ELISA: suitable, western blot: suitable

technique(s)

ELISA: suitable, western blot: suitable

technique(s)

ELISA: suitable, western blot: suitable

technique(s)

ELISA: suitable, western blot: suitable

species reactivity

mouse

species reactivity

mouse

species reactivity

mouse

species reactivity

guinea pig

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

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General description

Immunoglobulin G (IgG) is the most abundant glycoprotein antibody found in human serum. It is secreted by the B cells. IgG structure contains four polypeptide chains, which include two identical heavy (H) chains and two identical λ light (L) chains. These chains are inter-linked by disulfide bonds. IgG exists in four isotypes IgG1, IgG2, IgG3, and IgG4.

Application

Rabbit Anti-Mouse IgG Antibody, HRP conjugate has been used in western blotting. (1:2000)(1:200000) (1:5000)

Biochem/physiol Actions

Immunoglobulin G (IgG) aids in the activation of the complement system. It neutralizes virus particles and toxins. IgG facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). Maternal IgG is transferred to the fetus through the placenta that is crucial for protecting newborns against infectious diseases. Detection of IgG levels in severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2 infected patients can be a potential strategy to assess the severity and prognosis of coronavirus disease 2019 (COVID‐19).

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Elen Rizzi et al.
International journal of cardiology, 165(1), 165-173 (2011-09-16)
Increased oxidative stress upregulates matrix metalloproteinases (MMPs) and transforming grow factor (TGF-β), which are involved in hypertensive cardiac remodeling. We tested the hypothesis that tempol (an antioxidant) could prevent these alterations in two-kidney, one-clip (2K1C) hypertension. Sham-operated or hypertensive rats
Cristina Evangelisti et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(12), 4276-4287 (2009-08-29)
MicroRNAs are a class of sophisticated regulators of gene expression, acting as post-transcriptional inhibitors that recognize their target mRNAs through base pairing with short regions along the 3'UTRs. Several microRNAs are tissue specific, suggesting a specialized role in tissue differentiation
Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury.
Roger S Chung, Paul A Adlard, Justin Dittmann, James C Vickers, Meng Inn Chuah, Adrian K West
Journal of Neurochemistry null
Rita L Peruquetti et al.
PloS one, 7(8), e42695-e42695 (2012-08-18)
Spermatogenesis is a complex differentiation process that involves genetic and epigenetic regulation, sophisticated hormonal control, and extensive structural changes in male germ cells. RNA nuclear and cytoplasmic bodies appear to be critical for the progress of spermatogenesis. The chromatoid body
S B A Cau et al.
British journal of pharmacology, 164(2), 372-381 (2011-03-26)
Mounting evidence implicates matrix metalloproteinase (MMP) in the vascular dysfunction and remodelling associated with hypertension. We tested the hypothesis that treatment with pyrrolidine dithiocarbamate (PDTC), which interferes with NF-κB-induced MMPs gene transcription, could exert antihypertensive effects, prevent MMP-2 and MMP-9

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