MilliporeSigma
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C5VP001A

Millipore

Cellicon® Filter Assembly with Durapore® Membrane

filtration area 0.01 m2

All Photos(1)
Synonym(s):
Cellicon® Perfusion Filter with Durapore® Membrane

material

PET support
PVDF
polyester support

Quality Level

400

Agency

meets USP Biological Reactivity Test for class VI plastics (family component materials)

sterility

sterile; γ-irradiated (level of 25-40kGy)

flow rate measuring range

10 L/min (/m2)

parameter

1 psi max. reverse press. exposure at 25 °C
1-2.5 L process volume
15 psi at 25 °C (max. burst pressure)
5 psi max. inlet pressure at 25 °C

filtration area

0.01 m2

membrane filtration area

0.01 m2

pore size

5 μm pore size

storage temp.

15-25°C

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C5VP190A

Cellicon® Filter Assembly with Durapore® Membrane

material

PET support, PVDF , polyester support

material

PVDF membrane, polyester screen, polypropylene housing (polypropylene silicone), silicone O-ring

material

PVDF membrane, polyester screen, polypropylene housing (polypropylene silicone), silicone O-ring

material

PVDF membrane, polyester screen, polypropylene housing (polypropylene silicone), silicone O-ring

sterility

sterile; γ-irradiated (level of 25-40kGy)

sterility

non-sterile; γ-irradiated

sterility

non-sterile; γ-irradiated

sterility

non-sterile; γ-irradiated

parameter

1 psi max. reverse press. exposure at 25 °C, 1-2.5 L process volume, 15 psi at 25 °C (max. burst pressure), 5 psi max. inlet pressure at 25 °C

parameter

7.85 L/min-m2 flow rate

parameter

7.15 L/min-m2 flow rate

parameter

7.37 L/min-m2 flow rate

filtration area

0.01 m2

filtration area

0.2 m2

filtration area

0.8 m2

filtration area

1.9 m2

pore size

5 μm pore size

pore size

5.0 μm

pore size

5.0 μm

pore size

5.0 μm

storage temp.

15-25°C

storage temp.

-

storage temp.

-

storage temp.

-

General description

Housing/Overmold/ Assembly fittings/Single-use pump head: Polypropylene; Feed screen: Polyethylene terephthalate (PET); Polyester; Tubing: AdvantaFlex (Thermoplastic Elastomer), DOW Pharma 65; Feed screen: Polyethylene terephthalate (PET); Polyester; Pressure sensors: Polysulfone; Cable ties: Nylon
The Cellicon® Perfusion Filter is designed to meet your perfused seed train challenges. It is a flat sheet cell retention filter running in tangential flow filtration mode part of a single-use assembly. Perfusion operations deliver high-density cell cultures that alleviate the burden of processing large production bioreactor volumes while increasing manufacturing flexibility. Introducing perfusion to your seed train makes it possible to inoculate a higher quantity of cells for one or more production bioreactors, thus increasing process efficiency.

Application

Microfiltration
Seed Train Perfusion

Features and Benefits

High throughput. Predictable linear scale up from lab to manufacturing scale. Reliable and reproducible performance. Low crossflow and cell shear.

Other Notes

These products are manufactured in a facility which adheres to Good Manufacturing Practices.

Legal Information

CELLICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Durapore is a registered trademark of Merck KGaA, Darmstadt, Germany

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

Material Qualification Dossier

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Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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