PECAM-1 is a type I integral membrane glycoprotein, and a member of the immunoglobulin superfamily of cell surface receptors. PECAM-1 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctions. PECAM-1 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is important in cell-cell interaction, cell-matrix interaction and signal transduction.
CBL1337 recognizes mouse PECAM-1, a 130-140 kDa type 1 integral membrane glycoprotein. This antibody has been shown to inhibit the aggregation of L cells transfected with a variant form of PECAM-1 (DeLisser, 1993).
Mouse leukocyte cell line 32D
Flow Cytometry: = 1 μg per 10e6 cells in 100 μL volume
Immunohistochemistry: acteone fixed frozen tissue sections.
Optimal working dilutions must be determined by the end user.
Research Sub Category
This Anti-PECAM-1 Antibody, clone 390, FITC conjugated is validated for use in FC, IH for the detection of PECAM-1.
Purified immunoglobulin conjugated to fluorescein. Liquid in in phosphate buffered saline containing 0.1% sodium azide.
Storage and Stability
Maintain at 2°-8°C for up to 12 months from date of receipt. DO NOT FREEZE.
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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