CBL191
Anti-Complement C3a Antibody, clone H13
clone H13, Chemicon®, from mouse
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 μg | Check Cart for Availability | $585.00 |
About This Item
UNSPSC Code:
12352202
NACRES:
NA.41
eCl@ss:
32160702
Clone:
H13, monoclonal
Species reactivity:
guinea pig, rabbit, human
Application:
ELISA, IHC, WB
Citations:
3
$585.00
Check Cart for Availability
A recombinant, preservative-free antibody is available for your target. Try ZRB2418
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
H13, monoclonal
species reactivity
guinea pig, rabbit, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... C3(718)
Immunogen
Human complement component C3
Application
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
This Anti-Complement C3a Antibody, clone H13 is validated for use in ELISA, IH, WB for the detection of Complement C3a.
Biochem/physiol Actions
The antibody recognizes an epitope on the alpha-chain of Complement C3 (Western blot). The antibody inhibits the anaphylactic function of C3a: the capacity of C3a to induce serotonin release from thrombocytes in vitro is inhibited; similarly, treatment of C3a with the antibody inhibits the C3a-induced skin reaction in vivo. The antibody is, in combination with antibodies to the C3b fragment, an excellent control for distinguishing ubiquitous or nonspecifically bound native C3 from the biologically active C3 fragment. Nonactivated C3 still bears the C3a determinant, whereas activated C3 (C3b, C3d) is C3a-negative. It is therefore useful for immunopathological assays (demonstration of C3 deposition in biopsies) and for C3a assays.
Physical form
Format: Purified
Protein A purified immunoglobulin lyophilized from PBS, pH 7.4, containing 0.5% BSA and 0.09% sodium azide. Reconstitute with 1 mL distilled water.
Preparation Note
Maintain at 2°-8°C for up to 12 months from date of receipt.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
1 of 1
This Item | |||
|---|---|---|---|
| clone H13, monoclonal | clone 3E7, monoclonal | clone polyclonal | clone 5F9, monoclonal |
| species reactivity guinea pig, rabbit, human | species reactivity human, primate | species reactivity human | species reactivity human |
| biological source mouse | biological source mouse | biological source chicken | biological source mouse |
| antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form affinity isolated antibody | antibody form purified immunoglobulin |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in dry ice |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
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Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
Storage Class
11 - Combustible Solids
wgk
WGK 3
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Momar Ndao et al.
Journal of clinical microbiology, 48(4), 1139-1149 (2010-01-15)
More than 10 million people are thought to be infected with Trypanosoma cruzi, primarily in the Americas. The clinical manifestations of Chagas' disease (CD) are variable, but most subjects remain asymptomatic for decades. Only 15 to 30% eventually develop terminal
Quantitation of the anaphylatoxin C3a in the presence of C3 by a novel sandwich ELISA using monoclonal antibody to a C3a neoepitope.
Zilow, G, et al.
Journal of Immunological Methods, 121, 261-268 (1989)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| CBL191 | 04053252740466 |