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CC175

Sigma-Aldrich

Lung dECM Gel Hydrogel Kit

Synonym(s):
Lung dECM Gel Hydrogel Kit

biological source

Porcine

packaging

pkg of 1 kit

manufacturer/tradename

Sigma-Aldrich

growth mode

N/A

application(s)

cell culture | mammalian: suitable

shipped in

ambient

storage temp.

2-8°C

General description

The cellular microenvironment directly and indirectly effects cellular behavior via both biophysical and biochemical routes. The microenvironment is composed of extracellular matrix proteins (ECM), other surrounding cells, cytokines, growth factors, hormones, and other bioactive agents and nano/microscale mechanical properties such as physical tension/stiffness. Decellularization is the process used in biomedical engineering to isolate the native extracellular matrix (ECM) of a tissue from its inhabiting cells, leaving an ECM scaffold of the original tissue, which can be used in cell culture and tissue regeneration. Compared to other tumor derived basement membrane extracts (Matrigel@), these dECM hydrogel scaffolds can provide a more physiological environment with increased growth rates for cells without the use of any exogenous growth factors. Our tissue-specific dECM Gel Hydrogel Kits are a series of native decellularized extracellular matrix (ECM) protein solutions derived from a variety of non-diseased porcine organs (bone, heart, liver, kidney, intestine, skin and lung). These hydrogels can be used as traditional 2D ECM coatings or as hydrogels to encapsulate cells for 3D cell culture applications.

Application

pH: 2.0-3.0Gelation: Forms GelBiocompatibility: 90% Cell ViabilitySterility: No Fungi or Bacteria DetectedMycoplasma: NegativePRRS, PRV: Negative

Features and Benefits

Lung decellularized ECM scaffold for traditional 2D and 3D cell culture applications.

Storage and Stability

Store all components of the dECM Gel Hydrogel Kit at 2-8°C (do not freeze).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Corrosion

Signal Word

Warning

storage_class_code

8B - Non-combustible, corrosive hazardous materials

Certificate of Analysis

Certificate of Origin

Articles
Comparison of decellularized extracellular matrix (dECM) hydrogels to Matrigel® matrices for predictive 3D cell culture models
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Hydrogela are the most widely used systems for 3D cell culture. Learn more about this technology (what are hydrogels? How to chose?)
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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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