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CR0003L200

Millipore

Single-use 3L stirred tank bioreactor (green)

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32031690

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General description

A single-use, stirred tank bioreactor designed for the non-GMP cultivation of mammalian cell lines. Its rigid design includes a semi-hemispherical shaped polycarbonate vessel, a multi-port high-density polyethylene (HDPE) headplate, a scoping marine impeller, both open pipe and sintered spargers, weldable C-Flex tubing, and all necessary gas inlet and outlet filters. Because the vessel is molded component, additional ports were added below the minimum working volume level including, one luer actuated sample port, one liquid inlet/outlet port, two liquid addition lines, direct sparging lines and a harvest line. All gas and liquid addition ports located below the minimum working volume incorporate check valves to ensure uni-directional flow of gas or liquid. The CellReady 3L Bioreactor is preassembled, gamma irradiated and shipped ready to use.

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Articles

A step-by-step overview of suspension-based, transient transfection bioreactor process development and scaleup of lentivirus production.

This page describes the design attributes of the Cellicon® filter assembly for cell retention and how they simplify scale-up of intensified upstream processes.

How the Cellicon® filter and controller enables seamless adoption of a perfused N-1 seed train step into the cell expansion process.

This page describes the financial and operational advantages offered by the Cellicon® Cell Retention Device in an N-1 perfusion process at the 2,000 L scale in comparison to a cell retention device from another supplier.

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Related Content

The Mobius® iFlex Bioreactor family includes pilot, clinical and commercial manufacturing (50 – 2,000 L) single-use bioreactors that enable mammalian cell culturing capabilities from early process development through commercial batch production.

This technical article breaks down the adenovirus vaccine manufacturing process and provides a case study on developing an accelerated and cost-effective single-use adenoviral vector vaccine.

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