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GF167

Sigma-Aldrich

BMP-4 Protein, Human Recombinant

The Bone morphogenetic protein 4 (or BMP-4 protein) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood.

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Synonym(s):
BMP4, Bone morphogentic protein-4, DVR-4
eCl@ss:
32160405

Quality Level

100

Assay

>97% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI accession no.

NM_001202.3
NM_130850.2
NM_130851.2

UniProt accession no.

P12644

shipped in

dry ice

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BMP-6 Protein, Human Recombinant

assay

>97% (SDS-PAGE and HPLC)

assay

>98% (SDS-PAGE and HPLC)

assay

>98% (SDS-PAGE and HPLC)

assay

>95% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI accession no.

NM_001202.3, NM_130850.2, NM_130851.2

NCBI accession no.

NM_001202.3, NM_130850.2, NM_130851.2

NCBI accession no.

-

NCBI accession no.

-

UniProt accession no.

P12644

UniProt accession no.

P12644

UniProt accession no.

P12643

UniProt accession no.

P22004

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

General description

Bone morphogentic protein 4 (BMP-4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
Product Source: Hela Cells

Specificity

Cross Reactivty
None

Application

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

Quality

Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.

Physical form

Product is filtered through a 0.2 micron filter before lyophilization.

Storage and Stability

Store at -20°C for up to 6 months from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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25G
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