MilliporeSigma
All Photos(1)

Documents

GF312

Sigma-Aldrich

SCF Protein, Human Recombinant Animal Free

The Stem cell factor also known as ckit ligand, mast cell growth factor & steel factor (SLF), is a widely expressed 28-40kDa type I transmembrane glycoprotein. Recombinant animal free human SCF is manufactured using all non-animal reagents.

Sign Into View Organizational & Contract Pricing

Select a Size

Synonym(s):
Stem Cell Factor, ckit Ligand, Mast Cell Growth Factor, Stell Factor, MGF
eCl@ss:
32160405

recombinant

expressed in E. coli

Quality Level

Assay

>98% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
GF021GF304GF303
assay

>98% (SDS-PAGE and HPLC)

assay

>98% (SDS-PAGE and HPLC)

assay

>98% (SDS-PAGE and HPLC)

assay

>98% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 ng/μg Endotoxin (of SCF; 1EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI accession no.

NM_000899.3, NM_003994.4

NCBI accession no.

NM_000899.3, NM_003994.4

NCBI accession no.

NM_000757.3, NM_172210.1, NM_172211.1, NM_172212.1

NCBI accession no.

NM_000759.42, NM_172219.1, NM_172220.1

UniProt accession no.

P21583

UniProt accession no.

P21583

UniProt accession no.

P09603

UniProt accession no.

P09919

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

General description

Product Source: E. coli
Stem cell factor (SCF), also known as ckit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Specificity

Cross Reactivty
Monkey

Application

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

Quality

Bioactivity assay: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

Physical form

Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human SCF is manufactured using all non-animal reagents

Storage and Stability

Store at -20°C for up to 6 months from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service