HCCBP1MAG-58K
MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel - Cancer Multiplex Assay
Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.
Synonym(s):
human cancer biomarker immunoassay panel, luminex human circulating cancer biomarkers multiplex assay, millipore human circulating cancer biomarkers multiplex kit
About This Item
Recommended Products
Quality Level
species reactivity
human
manufacturer/tradename
Milliplex®
assay range
accuracy: 35-108%
standard curve range: 0.09-67 mU/mL
(β-HCG)
standard curve range: 0.7-500 pg/mL
(IL-6)
standard curve range: 1.3-1000 pg/mL
(IL-8, TNFα)
standard curve range: 2.7-2000 pg/mL
(TRAIL, TGF-α)
standard curve range: 6.9-5000 pg/mL
(SCF)
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex xMAP)
shipped in
wet ice
General description
MILLIPLEX® Circulating Cancer Biomarker Panel 1 is a 25-plex kit that can be used for the simultaneous quantification of any or all of the following analytes in serum, plasma and tissue/cell lysate and culture supernatant samples: AFP, CA125, CA15-3, CA19-9, CEA, CYFRA21-1, sFas, sFasL, FGF2, β-HCG, HE4, HGF, IL-6, IL-8, Leptin, MIF, Osteopontin, Prolactin, PSA (free), PSA (total), SCF, TGFα, TNFα, TRAIL and VEGF. Note that certain biomarkers are tumor specific, such as PSA, while others, such as IL-8, have been detected in many cancers. PSA (free) and PSA (total) cannot be plexed together. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Circulating Cancer
Specificity
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Application
- Analytes: α-Fetoprotein (AFP), CA125, CA15-3, CA19-9, CEA, CYFRA21-1, sFas (TNFRSF6), sFasL, FGF-2 (FGF-basic), β-HCG (HCGβ), HE4, HGF, IL-6, IL-8 (CXCL8), Leptin, MIF, Osteopontin (OPN), Prolactin, PSA (free)*, PSA (total)*, SCF, TGFα, TNFα, TRAIL (TNFSF10), VEGF.
- Note: Total PSA and Free PSA cannot be plexed together
- Recommended Sample Type: Human serum, plasma or tissue/cell culture supernatants or lysates
- Recommended Sample Dilution: 25 μL per well of 1:6 diluted plasma or serum, or 25 μL cell culture psaesaa sample undiluted or diluted in appropriate control medium
- Assay Run Time: Overnight (16-18 hr) at 2-8°C
- Research Category: Cancer
Features and Benefits
Packaging
Components
Human Circulating Cancer Biomarker Panel 1 Quality Controls 1 and 2 (HCC-6058)
Serum Matrix (HCP-SM)
Note: Contains 0.08% Sodium Azide
Set of one 96-Well Plate with 2 Sealers (MAG-PLATE)
Assay Buffer (L-AB)
Note: Contains 0.08% Sodium Azide
10X Wash Buffer (L-WB)
Note: Contains 0.05% Proclin
Human Circulating Cancer Biomarker Panel 1 Detection Antibodies (HCC-1058 or HCC-1058-2)
Streptavidin-Phycoerythrin (L-SAPE 4)
Bead Diluent (LBD-4)
Storage and Stability
Other Notes
Legal Information
Disclaimer
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Storage Class
10 - Combustible liquids
Certificates of Analysis (COA)
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Related Content
Cancer biomarker detection through MILLIPLEX® multiplex cancer assays can accelerate studies of tumorigenic processes helping advance cancer research.
Multiplex assays simplify cancer research by measuring multiple biomarkers simultaneously for various signaling pathways.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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