HCP4MG64KPX20BK

MILLIPLEX^® Human Cytokine/Chemokine Panel 4

Bulk (Space Saver) Premixed Human Cytokine/Chemokine 20-Plex Panel 4

• Synonym(s): Human cytokine multiplex kit, Luminex^® human cytokine immunoassay, Millipore human cytokine panel
• NACRES: NA.47
• UNSPSC Code: 12161503

Properties

• Product Name: MILLIPLEX^® Human Cytokine/Chemokine Panel 4,
• description: Bulk (Space Saver) Premixed Human Cytokine/Chemokine 20-Plex Panel 4
• species reactivity: human
• packaging: pkg of 1 ea
• manufacturer/tradename: Milliplex^®
• technique(s): multiplexing: suitable
• input: plasma; cell culture supernatant(s)
• detection method: fluorometric (Luminex^® xMAP^® technology)
• shipped in: wet ice
• storage temp.: 2-8°C

Description

General description

“Cytokine” is a general term used for a diverse group of soluble proteins and peptides which act as regulators under both normal and pathological conditions to modulate the functional activities of individual cells and tissues. These proteins also mediate direct interactions between cells and regulate processes taking place in the extracellular environment. The cytokine group of proteins includes lymphokines, interferons, colony stimulating factors and chemokines. Cytokine and chemokine research plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, as well as disease states such as inflammatory disease, allergic reactions, irritable bowel disease (IBD), sepsis, and cancer.

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 20 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: BAFF/Blys, BRAK/CXCL14, CCL28, CXCL16, HCC-4/CCL16, HMGB1, IFNβ, IL-14, IL-19, IL-24, IL-28B, IL-32α, IL-34, IL-35, IL-36β/IL-1F8, IL-37/IL-1F7, IL-38/IL-1F10, MIP-4, MPIF/CCL23, YKL40

Note: HMGB1 can be measured in serum and plasma samples only.Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

• Dynamic Range Optimization: Pre-verified 1:4 serum/plasma dilution minimizes matrix effects while maintaining sensitivity for both high-abundance (e.g., YKL-40) and low-level targets (e.g., IL-34).
• Pioneering Research Applications: Decode IL-38’s role in autoimmune regulation and IL-24’s dual pro-inflammatory/oncolytic effects. Investigate HMGB1 as a prognostic marker in critical care or YKL-40 in fibrotic disorders or map chemokine networks (e.g., CXCL16 in atherosclerosis, CCL23 in angiogenesis).
• Reduced Hands-On Time: Preconfigured reagents and intuitive protocols simplify high-throughput workflows.
• Adaptable Sensitivity: Tailor detection ranges via dilution to capture both abundant (e.g., BAFF) and rare (e.g., IFNβ) analytes.

Legal Information

Luminex is a registered trademark of Luminex Corporation

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Safety Information

• pictograms: GHS08,GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302 + H312 + H332,H317,H318,H373,H411
• pcodes: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• target_organs: Respiratory Tract
• Storage Class: 10 - Combustible liquids
• wgk: WGK 3