MAB1308

Mouse Anti-Human IgG2 Antibody, clone HP6002, Fc

Name: Mouse Anti-Human IgG2 Antibody, clone HP6002, Fc
Brand: MM
Price: 222 USD

clone HP6002, Chemicon^®, from mouse

Synonym(s):

Anti-Anti-CD32, Anti-Anti-CD32B, Anti-Anti-FCG2, Anti-Anti-FCGR2, Anti-Anti-FCGR2C, Anti-Anti-FcGRIIB, Anti-Anti-FcRII-c, Anti-Anti-FcgammaRIIb, Anti-Anti-IGFR2

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500 μG

$222.00

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.46

eCl@ss:

32160702

Key Documents

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Product Name

Mouse Anti-Human IgG2 Antibody, clone HP6002, Fc, clone HP6002, Chemicon^®, from mouse

isotype

IgG1

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

secondary antibodies

clone

HP6002, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon^®

technique(s)

ELISA: suitable
radioimmunoassay: suitable
western blot: suitable

NCBI accession no.

NM_001002273.1
NM_001002274.1
NM_001002275.1
NM_004001.3

UniProt accession no.

P31994

shipped in

wet ice

target post-translational modification

unmodified

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Show Differences

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This Item	MAB1307	MAB1312	SAB2500218
Sigma-Aldrich MAB1308 Mouse Anti-Human IgG2 Antibody, clone HP6002, Fc	Sigma-Aldrich MAB1307 Mouse Anti-Human IgG1 Antibody, clone HP6001, Fc	Sigma-Aldrich MAB1312 Mouse Anti-Human IgG4 Antibody, clone HP6023, Fc	Sigma-Aldrich SAB2500218 Anti-CD32/FCGR2B antibody produced in goat
species reactivity human	species reactivity human	species reactivity human	species reactivity human
technique(s) ELISA: suitable, western blot: suitable, radioimmunoassay: suitable	technique(s) ELISA: suitable, radioimmunoassay: suitable, western blot: suitable	technique(s) ELISA: suitable, radioimmunoassay: suitable, western blot: suitable	technique(s) immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
biological source mouse	biological source mouse	biological source mouse	biological source goat
antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form affinity isolated antibody
isotype IgG1	isotype IgG2b	isotype IgG3	isotype -
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in dry ice

Application

This Mouse anti-Human IgG2 Antibody, clone HP6002, Fc is validated for use in ELISA, RIA, WB for the detection of Human IgG2.

This antibody employed as both a capture antibody and a detection antibody for human IgG2 in enzyme linked immunosorbent assays, radio-immunoassay and EIA affinity immunoblots (Papadea et al., 1985; Hamilton, et al., 1987).

Final working dilutions must be determined by end user.

Biochem/physiol Actions

Human IgG2 Fc. ELISA Specificity: (Hamilton et al., 1987) human IgG subclass 1-0.02% human IgG subclass 2- 100% human IgG subclass 3- 0.01%

human IgG subclass 4- 0.01% Isoelectric Focusing: mean pI 7.1

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: 411462-200UG

Physical form

Format: Purified

Purified Immunoglobulin. Liquid in 0.02M Phosphate buffer, pH=7.6, 0.25M NaCl containing 0.1% sodium azide.

Preparation Note

Maintain at 2-8°C for up to one year in undiluted aliquots.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Monocyte differentiation in localized juvenile periodontitis is skewed toward the dendritic cell phenotype.

Suzanne E Barbour et al.

Infection and immunity, 70(6), 2780-2786 (2002-05-16)

Several lines of evidence indicate that the monocytes of subjects with localized juvenile periodontitis (LJP) are functionally distinct from cells of age- and race-matched nonperiodontitis (NP) subjects. Among the abnormalities are the propensity to secrete large amounts of prostaglandin E(2)

Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design.

Subhash Singh et al.

The Journal of infectious diseases, 190(5), 1010-1018 (2004-08-06)

Merozoite surface protein 3 (MSP3) is a target of antibody-dependent cellular inhibition (ADCI), a protective mechanism against Plasmodium falciparum malaria. From the C-terminal half of the molecule, 6 overlapping peptides were chosen to characterize human immune responses. Each peptide defined

Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria.

Elizabeth H Aitken et al.

eLife, 10 (2021-06-29)

Plasmodium falciparum causes placental malaria, which results in adverse outcomes for mother and child. P. falciparum-infected erythrocytes that express the parasite protein VAR2CSA on their surface can bind to placental chondroitin sulfate A. It has been hypothesized that naturally acquired

Toward the rational design of a malaria vaccine construct using the MSP3 family as an example: contribution of antigenicity studies in humans.

Corine G Demanga et al.

Infection and immunity, 78(1), 486-494 (2009-11-04)

Plasmodium falciparum merozoite surface protein (MSP3) is a main target of protective immunity against malaria that is currently undergoing vaccine development. It was shown recently to belong, together with MSP6, to a new multigene family whose C-terminal regions have a

Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3.

F Brière et al.

The Journal of experimental medicine, 179(2), 757-762 (1994-02-01)

During antigen-induced immune responses, human B cells switch isotype from immunoglobulin M (IgM)-IgD to IgG1-4, IgA1-2, or IgE. In the human, no cytokines have yet been demonstrated to act as switch factors for IgG1, IgG2, and IgG3. In this paper

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