MAB1345

Anti-Collagen Type VII Antibody, CT, clone LH7.2

Name: Anti-Collagen Type VII Antibody, CT, clone LH7.2
Brand: MM

ascites fluid, clone LH7.2, Chemicon^®

Synonym(s):

Anti-EBD1, Anti-EBR1, Anti-NDNC8

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Key Documents

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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

LH7.2, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon^®

technique(s)

immunocytochemistry: suitable

isotype

IgG

NCBI accession no.

NM_000094.3

UniProt accession no.

Q02388

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... COL7A1(1294)

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This Item	SAB4200686	C6805	MAB1340
Sigma-Aldrich MAB1345 Anti-Collagen Type VII Antibody, CT, clone LH7.2	Sigma-Aldrich SAB4200686 Anti-Collagen, Type VII antibody, Mouse monoclonal	Sigma-Aldrich C6805 Monoclonal Anti-Collagen, Type VII antibody produced in mouse	Sigma-Aldrich MAB1340 Anti-Collagen Type I Antibody, clone C11
clone LH7.2, monoclonal	clone LH7.2, monoclonal	clone LH7.2, monoclonal	clone C11, monoclonal
Gene Information human ... COL7A1(1294)	Gene Information human ... COL7A1(1294)	Gene Information human ... COL7A1(1294)	Gene Information human ... COL1A1(1277)
antibody form ascites fluid	antibody form purified immunoglobulin	antibody form ascites fluid	antibody form ascites fluid
biological source mouse	biological source mouse	biological source mouse	biological source mouse
species reactivity human	species reactivity human	species reactivity human, goat, marmoset, monkey, guinea pig, sheep, pig, bovine	species reactivity human
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 100

Immunogen

Collagen type VII.

Application

Anti-Collagen Type VII Antibody, C-terminus, clone LH7.2 is an antibody against Collagen Type VII for use in IC.

Immunohistochemistry.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Carboxy terminal peptide of type VII collagen.

Physical form

Ascites. Liquid with 0.1% sodium azide.

Preparation Note

Maintain at -20°C in convenient aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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related product

Product No.

Description

Pricing

ZRB1507

Anti-Collagen Type VII Antibody, clone 1E5 ZooMAb^® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination.

Dimitra Kiritsi et al.

The Journal of clinical investigation, 122(5), 1742-1746 (2012-04-03)

Spontaneous gene repair, also called revertant mosaicism, has been documented in several genetic disorders involving organs that undergo self-regeneration, including the skin. Genetic reversion may occur through different mechanisms, and in a single individual, the mutation can be repaired in

Distribution of basement membrane zone components in bullous lesions of subepidermal blistering diseases.

Satomi Hosoda et al.

The Journal of dermatology, 40(3), 211-212 (2013-01-09)

Cultured Epidermal Autografts from Clinically Revertant Skin as a Potential Wound Treatment for Recessive Dystrophic Epidermolysis Bullosa.

Wakana Matsumura et al.

The Journal of investigative dermatology, 139(10), 2115-2124 (2019-05-06)

Inherited skin disorders have been reported recently to have sporadic normal-looking areas, where a portion of the keratinocytes have recovered from causative gene mutations (revertant mosaicism). We observed a case of recessive dystrophic epidermolysis bullosa treated with cultured epidermal autografts

Type VII Collagen Expression in the Human Vitreoretinal Interface, Corpora Amylacea and Inner Retinal Layers.

Bart Wullink et al.

PloS one, 10(12), e0145502-e0145502 (2015-12-29)

Type VII collagen, as a major component of anchoring fibrils found at basement membrane zones, is crucial in anchoring epithelial tissue layers to their underlying stroma. Recently, type VII collagen was discovered in the inner human retina by means of

High concordance between clinical diagnosis of epidermolysis bullosa and immunofluorescence with a small, well-matched antibody panel.

Irene Meester et al.

The Australasian journal of dermatology, 59(1), 73-76 (2017-07-15)

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