MAB1383

Anti-Integrin α4 Antibody, clone HP2/1

clone HP2/1, Chemicon^®, from mouse

• Synonym(s): CD49d
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: HP2/1, monoclonal
• species reactivity: human, bovine, rat
• manufacturer/tradename: Chemicon^®
• technique(s): flow cytometry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• isotype: IgG1
• NCBI accession no.: NM_000885.4
• UniProt accession no.: P13612
• shipped in: dry ice
• Gene Information: human ... ITGA4(3676) ; rat ... Itga4(311144)

Description

Specificity

Recognizes the 80kDa alpha chain of VLA-4. Reacts with monocytes, T cells, B cells, thymocytes and Langerhans cells. Can be used in basic studies of VLA-4 mediated adhesion and its interaction with the VCAM-1 structure. HP2/1 inhibits cell binding to soluble VCAM-1.

Immunogen

JM leukemia line

Application

Detect Integrin α4 using this Anti-Integrin α4 Antibody, clone HP2/1 validated for use in FC, IP, IH.

Flow cytometry: 1μg/5 X 10E5 cells

Immunohistology on frozen tissue sections

Immunoprecipitation

Optimal working dilutions must be determined by end user.

Research Category
Cell Structure

Research Sub Category
Integrins

Linkage

Replaces: 04-1131

Physical form

Format: Purified

Purified immunoglobulin - Ig fraction. Liquid in Phosphate Buffered Saline, pH 7.4 with 0.1% Sodium Azide.

Storage and Stability

Store at -20°C in undiluted aliquots. May be stored at 2-8°C for short term use. Avoid repeated freeze-thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable