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MAB336

Sigma-Aldrich

Anti-Syntaxin Antibody, clone SP8

ascites fluid, clone SP8, Chemicon®

Synonym(s):

Syntaxin 1A, Neuron-specific Antigen HPC-1, STX1A

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

SP8, monoclonal

species reactivity

hamster, human, pig, rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... STX1A(6804)

Related Categories

Specificity

Syntaxin (34-36 kDa). Reacts with syntaxin expressed in bacterial systems.

Immunogen

Crude synaptic immunoprecipitate (Human).

Application

Immunohistochemistry at >1:100-1:200.

Formalin fixed (fixed <4 weeks)

Western blotting at 1:100-1:10,000.

ELISA at 1:500

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
This Anti-Syntaxin Antibody, clone SP8 is validated for use in ELISA, WB, IH for the detection of Syntaxin.

Physical form

Liquid with 0.1% Sodium Azide.

Storage and Stability

Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice.
Hong, HK; Chakravarti, A; Takahashi, JS
Proceedings of the National Academy of Sciences of the USA null
Liza Barki-Harrington et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(29), 9219-9226 (2009-07-25)
We aimed to test whether tyrosine phosphorylation of the NMDA receptor (NMDAR) in the insular cortex is necessary for novel taste learning. We found that in rats, novel taste learning leads to elevated phosphorylation of tyrosine 1472 of the NR2B
S Liu et al.
Neuroscience, 146(4), 1677-1688 (2007-05-01)
Serotonin (5-HT) action via the 5-HT(2C) receptor (5-HT(2C)R) provides an important modulatory influence over neurons of the prefrontal cortex (PFC), which is critically involved in disorders of executive function including substance use disorders. In the present study, we investigated the
P Osten et al.
Neuron, 21(1), 99-110 (1998-08-11)
In this study, we demonstrate specific interaction of the GluR2 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit C-terminal peptide with an ATPase N-ethylmaleimide-sensitive fusion protein (NSF) and alpha- and beta-soluble NSF attachment proteins (SNAPs), as well as dendritic colocalization of these proteins. The
Noelle C Anastasio et al.
Journal of neurochemistry, 113(6), 1504-1515 (2010-03-30)
The action of serotonin (5-HT) at the 5-HT(2C) receptor (5-HT(2C)R) in cerebral cortex is emerging as a candidate modulator of neural processes that mediate core phenotypic facets of several psychiatric and neurological disorders. However, our understanding of the neurobiology of

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