MAB3872

Anti-PPAR γ Antibody, isoform 1&2

ascites fluid, clone 1H4, Chemicon^®

• Synonym(s): PPAR gamma
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: 1H4, monoclonal
• Application: ELISA; immunocytochemistry; western blot
• Species reactivity: human, mouse
• Citations: 14
• Technique(s): ELISA: suitable; immunocytochemistry: suitable; western blot: suitable
• Uniprot accession no.: P37231

Properties

• Product Name: Anti-PPAR γ Antibody, isoform 1&2, ascites fluid, clone 1H4, Chemicon^®
• biological source: mouse
• conjugate: unconjugated
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: 1H4, monoclonal
• species reactivity: human, mouse
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable; immunocytochemistry: suitable; western blot: suitable
• isotype: IgG1
• NCBI accession no.: NM_005037.5; NM_015869.4; NM_138711.3; NM_138712.3
• UniProt accession no.: P37231
• shipped in: wet ice
• target post-translational modification: unmodified
• Quality Level: 100
• Gene Information: human ... PPARG(5468)

Description

Analysis Note

Control
THP-1 cell lysate, 3T3-L1 cell lysate or U-937 cell lysate

Application

Anti-PPAR γ Antibody, isoform 1&2 is a Mouse Monoclonal Antibody for detection of PPAR gamma also known as Peroxisome Proliferator Activated Receptor γ & has been validated in ELISA, ICC & WB.

Biochem/physiol Actions

Reacts with human PPAR gamma2. The antibody also reacts with PPAR gamma1 due to immunogen sequence homology. The immunogen shows no homology with PPAR alpha or PPAR beta.

General description

67 kDa

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: a, b and g. PPARg stimulates lipolysis of circulating triglycerides and the subsequent uptake of fatty acids into adipose cells. PPARs can bind to DNA only as a heterodimer with the retinoid X receptor (RXR).

Immunogen

Epitope: isoform 1&2

Synthetic peptide from amino acids 107-121 of human PPAR gamma2.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable