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MilliporeSigma

MAB4388

Mouse Anti-Stella Antibody

clone 3H5.2, Chemicon®, from mouse

Synonym(s):

Anti-Anti-Pgc7, Anti-Anti-STELLA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
3H5.2, monoclonal
Application:
ELISA, ICC
Citations:
13

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3H5.2, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunocytochemistry: suitable

input

sample type: human embryonic stem cell(s)
sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Dppa3(73708)

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T5326C3367WH0004254M1
species reactivity

mouse, human

species reactivity

rat, hamster, chicken, human, bovine, canine, Xenopus, mouse

species reactivity

mouse, human

species reactivity

human

clone

3H5.2, monoclonal

clone

GTU-88, monoclonal

clone

7-1H, monoclonal

clone

3E10, monoclonal

Gene Information

mouse ... Dppa3(73708)

Gene Information

human ... TUBG1(7283)
mouse ... Tubg1(103733)
rat ... Tubg1(252921)

Gene Information

human ... CIITA(4261)
mouse ... Ciita(12265)

Gene Information

human ... KITLG(4254)

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody form

purified antibody (purified from hybridoma cell culture)

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

UniProt accession no.

Q6W0C5

UniProt accession no.

P23258

UniProt accession no.

P33076

UniProt accession no.

P21583

General description

Stella is specifically expressed by oocytes, pluripotent cells and primordial germ cells at the time of their emergence in gastrulating embryos, and is an important maternal factor in the cleavage stages of mouse embryos (Bortvin, 2004). The requirement for stella in germ cell specification remains controversial, however, most embryos from stella deficient mice failed to develop normally and rarely reach the blastocyst stage (Bortvin, 2004; Payer, 2003). The stella gene encodes a protein with an SAP-like domain and splicing factor motif-like structure, suggesting possible roles in chromosomal organization and RNA processing (Payer, 2003).

Application

Mouse Anti-Stella Antibody detects level of Stella & has been published & validated for use in ELISA & IC.
Research Category
Stem Cell Research
Research Sub Category
Pluripotent & Early Differentiation

Biochem/physiol Actions

Reacts with stella from human and mouse.

Physical form

Format: Purified
Purified Immunoglobulin presented as a liquid in PBS with 0.1% sodium azide.

Preparation Note

Maintain refrigerated at 2-8C in undiluted aliquots for up to 12 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pengxiang Wang et al.
Cell proliferation, 57(1), e13533-e13533 (2023-08-04)
Primordial germ cells (PGCs) are the germline precursors that give rise to oocytes and sperm, ensuring the continuation of life. While the PGC specification is extensively studied, it remains elusive how the PGC population is sustained and expanded after they
Maurizio Zuccotti et al.
BMC developmental biology, 8, 97-97 (2008-10-08)
The maternal contribution of transcripts and proteins supplied to the zygote is crucial for the progression from a gametic to an embryonic control of preimplantation development. Here we compared the transcriptional profiles of two types of mouse MII oocytes, one
Xun Xu et al.
Nature materials (2024-08-13)
Naive pluripotent stem cells have the highest developmental potential but their in vivo existence in the blastocyst is transient. Here we report a blastocyst motif substrate for the in vitro reversion of mouse and human pluripotent stem cells to a
Katja Linher et al.
PloS one, 4(12), e8263-e8263 (2009-12-17)
We have previously demonstrated that stem cells isolated from fetal porcine skin have the potential to form oocyte-like cells (OLCs) in vitro. However, primordial germ cells (PGCs), which must also be specified during the stem cell differentiation to give rise
Wenlin Li et al.
Methods in molecular biology (Clifton, N.J.), 1074, 31-37 (2013-08-27)
The derivation of mouse embryonic stem cells (mESCs) from the inner cell mass (ICM) of mouse preimplantation blastocysts has provided tremendous opportunities in exploring mammalian development and pluripotent stem cell biology (Martin, Proc Natl Acad Sci U S A 78(12):7634-7638

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