MAB5492

Anti-Huntingtin Disease (HD/HTT) Antibody

CHEMICON^®, mouse monoclonal, 2B4

• Synonym(s): Anti-Huntingtin, Anti-Huntingtin Antibody, Detection Antibody
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• Clone: 2B4, monoclonal
• Species reactivity: human
• Application: ELISA, ICC, IHC, WB
• Citations: 51

Properties

• Product Name: Anti-Huntingtin Antibody, a.a. 1-82, ascites fluid, clone 2B4, Chemicon^®
• biological source: mouse
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: 2B4, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
• isotype: IgG1
• NCBI accession no.: NM_002111.6
• UniProt accession no.: P42858
• shipped in: dry ice
• target post-translational modification: unmodified
• Quality Level: 100
• Gene Information: human ... HTT(3064), SLC6A4(6532)

Description

General description

348 kDa

Immunogen

Epitope: a.a. 1-82

Recombinant human huntingtin, amino acids 1-82.

Application

Anti-Huntingtin Antibody, a.a. 1-82 is an antibody against Huntingtin for use in ELISA, IC, IH & WB.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Western blot: 1:500-1:5,000

Immunocytochemistry (1): 1:500-1:5,000

Immunohistochemistry (1,2): 1:500-1:5,000

ELISA: 1:500-1:5,000

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts huntingtin protein, amino acids 1-82. The antibody recognizes wild type and mutant huntingtin.

Physical form

Ascites fluid containing no preservatives.

Unpurified

Preparation Note

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Normal human cerebral cortex lysate, Mouse brain cortex samples from HD or wild type mice

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable