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MAB5618

Sigma-Aldrich

Anti-Serotonin Transporter Antibody

ascites fluid, Chemicon®

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Synonym(s):
SERT
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

monoclonal

species reactivity

primate, human

should not react with

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

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This Item
AB9726AB1594PMAB2170
antibody form

ascites fluid

antibody form

serum

antibody form

affinity purified immunoglobulin

antibody form

ascites fluid

clone

monoclonal

clone

polyclonal

clone

polyclonal

clone

HU-4E6, monoclonal

species reactivity

primate, human

species reactivity

mouse, rat

species reactivity

rat, human

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

ELISA: suitable, western blot: suitable

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), immunoprecipitation (IP): suitable, western blot: suitable

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Specificity

Serotonin Transporter, human and non-human primate.

Immunogen

Synthetic peptide from human serotonin transporter.

Application

Anti-Serotonin Transporter Antibody detects level of Serotonin Transporter & has been published & validated for use in IH.
Immunohistochemistry: 1:500-1:1,000 on 10% formalin fixed, paraffin embedded tissue from human Medulla oblongata. Suggested antigen retrieval method is Heat Induced Epitope Retrieval (HIER): Citrate Buffer pH 6.0.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Physical form

Ascites

Storage and Stability

Maintain at -20degC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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C H Lew et al.
Molecular autism, 11(1), 12-12 (2020-02-07)
Williams syndrome (WS) and autism spectrum disorder (ASD) are neurodevelopmental disorders that demonstrate overlapping genetic associations, dichotomous sociobehavioral phenotypes, and dichotomous pathological differences in neuronal distribution in key social brain areas, including the prefrontal cortex and the amygdala. The serotonergic
E C C Castro et al.
Canadian respiratory journal, 2017, 9064046-9064046 (2017-03-21)
Introduction. Failure of the vascular pulmonary remodeling at birth often manifests as pulmonary hypertension (PHT) and is associated with a variety of neonatal lung disorders including a uniformly fatal developmental disorder known as alveolar capillary dysplasia with misalignment of pulmonary
Danielle N Jones et al.
The Journal of comparative neurology, 529(7), 1659-1668 (2020-10-07)
The genus Macaca is an ideal model for investigating the biological basis of primate social behavior from an evolutionary perspective. A significant amount of behavioral diversity has been reported among the macaque species, but little is known about the neural
Jonas Woll Jørandli et al.
American journal of physiology. Gastrointestinal and liver physiology, 319(6), G761-G768 (2020-09-25)
Serotonin is a highly conserved and ubiquitous signaling molecule involved in a vast variety of biological processes. A majority of serotonin is produced in the gastrointestinal epithelium, where it is suggested to act as a prominent regulatory molecule in the
Smriti Patodia et al.
Brain pathology (Zurich, Switzerland), 32(5), e13074-e13074 (2022-04-29)
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for SUDEP. Reduced medullary serotonergic neurones, modulators of respiration in response to hypercapnia, were reported in

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