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MAB80138

Sigma-Aldrich

Anti-Human Metapneumovirus Antibody, clone 507

clone 507, Chemicon®, from mouse

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Synonym(s):
hMPV
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

507, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
western blot: suitable

isotype

IgG2a

shipped in

wet ice

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antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

clone

507, monoclonal

clone

406, monoclonal

clone

67, monoclonal

clone

140, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, flow cytometry: suitable, immunofluorescence: suitable, western blot: suitable

technique(s)

ELISA: suitable, flow cytometry: suitable

technique(s)

ELISA: suitable, flow cytometry: suitable, immunofluorescence: suitable

technique(s)

ELISA: suitable, flow cytometry: suitable, immunofluorescence: suitable

General description

Human metapneumovirus (hMPV) is a member of the pneumovirinae subfamily of paramyxoviruses, first described in 2001 from pediatric respiratory specimens in the Netherlands. It is an enveloped pleomorphic virus with a single negative-strand RNA genome. Two major serotypes, A and B, have been described. Several studies identified hMPV in specimens worldwide, and estimated that by age 5 years 70% of children have developed antibodies to hMPV.

Specificity

Recognizes the nuclear protein. Reactive with all hMPV sub-types; A1, A2, B1, B2.

Application

Detect Human Metapneumovirus using this Anti-Human Metapneumovirus Antibody, clone 507 validated for use in ELISA, FC, IF & WB.

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Xiaoyan Li et al.
Intervirology, 58(6), 403-412 (2016-04-21)
No licensed vaccines or therapeutic agents for human metapneumovirus (hMPV) infection exist to date. We aimed to construct a multi-epitope peptide (MEP) of hMPV to show promising results for epitope-based vaccine development. Six independent algorithms were screened to predict B-cell
Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999.
Chung-Guei Huang,Kuo-Chien Tsao,Tzou-Yien Lin,Yhu-Chering Huang,Li-Ang Lee,Tzu-Hou Chen et al.
Archives of Virology null
Simon Loevenich et al.
Mediators of inflammation, 2019, 4964239-4964239 (2019-11-07)
Human metapneumovirus (HMPV) may cause severe respiratory disease. The early innate immune response to viruses like HMPV is characterized by induction of antiviral interferons (IFNs) and proinflammatory immune mediators that are essential in shaping adaptive immune responses. Although innate immune
Youxian Li et al.
Scientific reports, 8(1), 883-883 (2018-01-19)
Thymic stromal lymphopoietin (TSLP) is associated with several allergic diseases including asthma. Two isoforms of TSLP exist in humans, a long form (lfTSLP) and a short form (sfTSLP), displaying distinct immunological functions. Recently, TSLP was found to be upregulated in
Analysis of the genomic sequence of a human metapneumovirus
van den Hoogen, Bernadette G, et al
Virology, 295, 119-132 (2002)

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