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MAB8905

Sigma-Aldrich

Anti-Measles Blend Antibody, hemagglutinin, clones CV1, CV4

ascites fluid, Chemicon®, from mouse

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Synonym(s):
Rubeola
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

clone

CV1, monoclonal
CV4, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)

isotype

IgG1

shipped in

wet ice

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antibody form

ascites fluid

antibody form

ascites fluid

antibody form

purified antibody

antibody form

purified antibody

clone

CV1, monoclonal, CV4, monoclonal

clone

CV1, monoclonal, CV4, monoclonal, CV8, monoclonal, CV9, monoclonal

clone

CV8, monoclonal, CV9, monoclonal

clone

83KKII, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable (paraffin)

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

ELISA: suitable, immunofluorescence: suitable

Specificity

A blend of two monoclonal antibodies that recognize the measles hemagglutinin protein by indirect immunofluorescence.

Immunogen

Epitope: hemagglutinin
Hemagglutinin protein obtained from Chicago wild type strain of measles

Application

Indirect immunofluorescence at 1:100-1:1,000 using acetone fixation.

Immunohistochemistry on paraffin embedded sections (Grote et al., 2001).



Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Measles Blend Antibody, hemagglutinin, clones CV1, CV4 is validated for use in IF, IH(P) for the detection of Measles Blend.

Physical form

Liquid ascites fluid containing no preservatives.

Storage and Stability

Maintain at -20°C in convenient aliquots for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Live attenuated measles virus induces regression of human lymphoma xenografts in immunodeficient mice.
Grote, D, et al.
Blood, 97, 3746-3754 (2001)
Michael N Ha et al.
Journal of virology, 91(23) (2017-09-15)
The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-phenylacetyl amino-benzamide (AS-48) have similar efficacies in blocking membrane fusion and syncytium formation mediated by measles virus (MeV). Other homologues, such as Z-d-Phe, are less effective but may act through the
The measles virus fusion protein transmembrane region modulates availability of an active glycoprotein complex and fusion efficiency.
Muhlebach, MD; Leonard, VH; Cattaneo, R
Journal of virology null
The measles virus hemagglutinin stalk: structures and functions of the central fusion activation and membrane-proximal segments.
Navaratnarajah, CK; Kumar, S; Generous, A; Apte-Sengupta, S; Mateo, M; Cattaneo, R
Journal of virology null
Dynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (SLAM, CD150).
Navaratnarajah, CK; Vongpunsawad, S; Oezguen, N; Stehle, T; Braun, W; Hashiguchi et al.
The Journal of Biological Chemistry null

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