Interleukin-1 (IL-1) is a cytokine that is thought to be connected to neurodegeneration and in central nervous system-mediated defense reactions to inflammation. Interleukin-1 beta (IL-1B) maintains mitogen-induced proliferation, IL-2 production and expression of IL-2R. IL-1 beta also seems to have the ability to boost the number of cells that move into the G1 phase of the cell cycle. IL-1 beta also has the capacity to stimulate apoptosis on normal human fetal membranes. IL-1 beta may play an important role in inflammation regulating cytokine networks.
Full length recombinant protein corresponding to human Interleukin-1 beta.
Anti-Interleukin-1 beta (IL-1B) Antibody, clone 4A7 is an antibody against Interleukin-1 beta (IL-1B) for use in WB.
Research Sub Category
Cytokines & Cytokine Receptors
Luminex Assay Analysis: A previous lot was used by an independent laboratory in Luminex (Dr. Gerard Zurawski, Baylor Institute for Immunology Research, Dallas, TX).
Inflammation & Immunology
Evaluated by Western Blot in lysate from cells expressing human Interleukin-1 beta recombinant protein.
Western Blot Analysis: 0.5 µg/mL of this antibody detected 10 µg of human Interleukin-1 beta recombinant protein.
~17 kDa observed
Replaces: 04-462; MABF22
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Human Interleukin-1 beta recombinant protein
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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