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MABN287

Sigma-Aldrich

Anti-ABCA4 Antibody, clone 5D7.1

clone 5D7.1, from mouse

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Synonym(s):
Retinal-specific ATP-binding cassette transporter, ATP-binding cassette sub-family A member 4, RIM ABC transporter, RIM protein, RmP, Stargardt disease protein
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

5D7.1, monoclonal

species reactivity

human

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ABCA4(24)

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This Item
MABN1775MABN2439MMABN893
Anti-ABCA4 Antibody, clone 5D7.1 clone 5D7.1, from mouse

MABN287

Anti-ABCA4 Antibody, clone 5D7.1

Anti-ABCA4 Antibody, clone TMR1 clone TMR1, from mouse

MABN1775

Anti-ABCA4 Antibody, clone TMR1

Anti-ABCA4 Antibody, clone 3F4 clone 3F4, from mouse

MABN2439M

Anti-ABCA4 Antibody, clone 3F4

clone

5D7.1, monoclonal

clone

TMR1, monoclonal

clone

3F4, monoclonal

clone

MAB198-7, monoclonal

species reactivity

human

species reactivity

human, mouse

species reactivity

bovine, human, mouse

species reactivity

mouse, human

Gene Information

human ... ABCA4(24)

Gene Information

human ... ABCA4(24)

Gene Information

human ... ABCA4(24)

Gene Information

bovine ... Abca1(535379)

biological source

mouse

biological source

mouse

biological source

mouse

biological source

rat

shipped in

wet ice

shipped in

wet ice

shipped in

-

shipped in

dry ice

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General description

Retinal-specific ATP-binding cassette transporter encoded by the gene ABCA4 plays a critical role in the transport of retinoid substrates from the extracellular or intradiscal rod cell membranes to the cytoplasmic membrane surface for processing ultimately into vitamin A and then transferred to the retinal pigment epithelium where it is converted to 11-cis-retinal that active component needed for vision. ABCA4 is localized to the outer segments of rods and cones with a million copies per photoreceptor. ABCA4 is retinal specific protein. Mutations in ABCA4 are linked to several eye-related genetic diseases, such as forms of macular degeneration called Stargardt disease and ARMD2, as well as Retinitis pigmentosa 19, and Cone-rod dystrophy 3.

Immunogen

Recombinant protein corresponding to human ABCA4.

Application

Anti-ABCA4 Antibody, clone 5D7.1 | MABN287 is an antibody against ABCA4 Antibody for use in Western Blotting, Immunohistochemistry (Paraffin).
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected ABCA4 in human retina tissue.

Quality

Evaluated by Western Blotting in Y79 cell lysate.

Western Blotting Analysis: 5.0 µg/mL of this antibody detected ABCA4 in 200 µg of Y79 cell lysate.

Target description

~275 kDa observed

Physical form

Format: Purified

Other Notes

Concentration: Please refer to lot specific datasheet.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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