MABN665

Anti-Synaptotagmin-7 Antibody, clone N275/14

clone N275/14, from mouse

• Synonym(s): Synaptotagmin-7, Synaptotagmin VII, SytVII
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: N275/14, monoclonal
• species reactivity: mouse, human, rat
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgG2bκ
• NCBI accession no.: NP_061271
• UniProt accession no.: Q9R0N7
• shipped in: wet ice
• Gene Information: human ... SYT7(9066)

Description

General description

Synaptotagmin-7 is also referred to as Synaptotagmin VII (SytVII) and is a member of the synaptotagmin family of transmembrane transporters. Synaptotagmin-7 is involved in plasma membrane repair, and possibly Ca2+-dependent exocytosis and traffiking of secretory vesicles.

Specificity

This antibody recognizes the cytoplasmic C2A domain of Synaptotagmin-7. This antibody does not cross react with Synaptotagmin-6 or other Synaptotagmins (Prof. J. Trimmer, University of California, Davis.).

Immunogen

Epitope: Cytoplasmic C2A domain

Recombinant protein corresponding to the cytoplasmic C2A domain of mouse Synaptotagmin-7.

Application

Anti-Synaptotagmin-7 Antibody, clone N275/14 is a highly specific mouse monoclonal antibody, that targets Synaptotagmin & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Synaptotagmin-7 in human thalamus tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Synaptotagmin-7 in 10 µg of mouse brain tissue lysate.

Target description

~ 45 kDa observed. Uncharacterized band(s) may appear in some lysates.

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse brain tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable