It measures all three isoforms (288, 300, and 315).
MCVD2MAG-77K
MILLIPLEX® Mouse Cardiovascular Disease (CVD) Magnetic Bead Panel 2 - Cardiovascular Disease Multiplex Assay
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About This Item
UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
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species reactivity
mouse
Quality Level
manufacturer/tradename
Milliplex®
assay range
accuracy: 84-106%
standard curve range: 137-100,000 pg/mL
(CD40L)
standard curve range: 14-10,000 pg/mL
(Endocan-1)
standard curve range: 274-200,000 pg/mL
(Follistatin)
standard curve range: 34-25,000 pg/mL
(CXCL16, Oncostatin M)
standard curve range: 4-3,000 pg/mL
(PIGF-2)
standard curve range: 686-500,000 pg/mL
(LIGHT, Troponin I)
standard curve range: 69-50,000 pg/mL
(Troponin T)
inter-assay cv: <20%
intra-assay cv: <10%
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex xMAP)
shipped in
wet ice
Related Categories
General description
Cardiovascular disease (CVD), particularly atherosclerotic vascular disease, is a leading cause of global mortality, accounting for 30% of all global deaths (WHO). Inflammatory mechanisms play a vital role in the initiation, maintenance, and progression of vascular disease with a strong correlation between inflammatory markers and prognosis in acute and chronic coronary artery disease. Numerous studies have demonstrated an association of obesity and diabetes with cardiovascular risk
factors.
MILLIPLEX® Mouse CVD Panel 2 is a 9 plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum, plasma, or tissue culture samples: sCD40L, CXCL16, Endocan-1, Follistatin, LIGHT, Oncostatin M, PlGF-2, Troponin I and Troponin T. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cardiovascular
factors.
MILLIPLEX® Mouse CVD Panel 2 is a 9 plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum, plasma, or tissue culture samples: sCD40L, CXCL16, Endocan-1, Follistatin, LIGHT, Oncostatin M, PlGF-2, Troponin I and Troponin T. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cardiovascular
The MILLIPLEX® MAP Mouse Cardiovascular Disease Panel 2 is used for the simultaneous quantification of any of the following analytes in serum, plasma, or culture supernatant samples: sCD40L, CXCL16, Endocan-1, Follistatin, LIGHT, Oncostatin M, PlGF-2, Troponin I, Troponin T.
Specificity
Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
Application
- Analytes: sCD40L, CXCL16, Endocan-1 (ESM-1), Follistatin, LIGHT, Oncostatin M (OSM), , Placental Growth Factor 2 (PIGF-2), Troponin I (TnI), Troponin T (TnT)
- Recommended Sample Type: Mouse serum, plasma, or cell/tissue culture supernatants or lysates
- Recommended Sample Dilution: 10 μL per well of undiluted serum or plasma; cell/tissue culture supernatants may require dilution in appropriate control medium
- Assay Run Time: Overnight (16-18 hours) at 2-8°C
- Research Category: Cardiovascular Disease
- Research Subcategory: Metabolism
Features and Benefits
Design your multiplex kit by choosing available analytes within this panel.
Packaging
Everything you need in a single kit.
Components
Mouse CVD Panel 2 Standard, 1 vial, lyophilized
Mouse CVD Panel 2 Quality Control 1, 1 vial, lyophilized
Mouse CVD Panel 2 Quality Control 2, 1 vial, lyophilized
Serum Matrix (0.08% Sodium Azide), 1 vial, lyophilized
Assay Buffer, 1 bottle, 30 mL
Bead Diluent, 1 bottle, 4 mL
Wash Buffer, 10X (0.05% Proclin), 2 bottles, 30 mL ea
Mouse CVD Panel 2 Detection Antibodies, 1 bottle, 5.5 mL
Streptavidin-Phycoerythrin, 1 bottle, 5.5 mL
Mixing Bottle, 1 bottle
Sample Plate, 96 well format, 1 plate
2 Foil Plate Sealers
Mouse CVD Panel 2 Quality Control 1, 1 vial, lyophilized
Mouse CVD Panel 2 Quality Control 2, 1 vial, lyophilized
Serum Matrix (0.08% Sodium Azide), 1 vial, lyophilized
Assay Buffer, 1 bottle, 30 mL
Bead Diluent, 1 bottle, 4 mL
Wash Buffer, 10X (0.05% Proclin), 2 bottles, 30 mL ea
Mouse CVD Panel 2 Detection Antibodies, 1 bottle, 5.5 mL
Streptavidin-Phycoerythrin, 1 bottle, 5.5 mL
Mixing Bottle, 1 bottle
Sample Plate, 96 well format, 1 plate
2 Foil Plate Sealers
Storage and Stability
Recommended storage for kit components is 2 - 8°C.
Other Notes
Please contact Technical Service for linearity of dilution.
Sensitivity: See kit protocol for individual analytes sensitivities.
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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David Sánchez-Infantes et al.
Obesity (Silver Spring, Md.), 25(1), 85-93 (2016-10-06)
Since oncostatin m (OSM) is elevated in adipose tissue in conditions of obesity and type 2 diabetes in mice and humans, the aim of this study was to determine whether this cytokine plays a crucial role in the impairment of
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Can you provide the epitope for the follistatin antibody used in this Milliplex kit? I'm trying to determine which follistatin isoforms may be detected using this kit.
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