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MilliporeSigma

MKI1MAG-94K

Millipore

MILLIPLEX® Mouse Kidney Injury Magnetic Bead Panel 1 - Toxicity Multiplex Assay

The analytes available for this multiplex kit are: β-2-Microglobulin, IP-10, KIM-1, Renin, TIMP-1, VEGF (for urine samples) or IP-10, KIM-1, Renin, and TIMP-1 (for serum/plasma samples).

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84

To order a Milliplex® kit, please search for your analyte of interest.

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Quality Level

species reactivity

mouse

manufacturer/tradename

Milliplex®

assay range

accuracy: 73-98%
sensitivity: 0.001-0.041 ng/mL
(MinDC+2SD)

standard curve range: 0.001-1 ng/mL
(VEGF)

standard curve range: 0.005-5 ng/mL
(IP-10)

standard curve range: 0.01-15 ng/mL
(KIM-1)

standard curve range: 0.02-25 ng/mL
(TIMP-1)

standard curve range: 0.05-50 ng/mL
(β-2-Microglobulin)

standard curve range: 0.05-50 ng/mL
(Renin)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

shipped in

wet ice

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This Item
MAP2MAG-76KHKI5MAG-99KMADKMAG-71K
species reactivity

mouse

species reactivity

mouse

species reactivity

human

species reactivity

mouse

assay range

accuracy: 73-98%, standard curve range: 0.001-1 ng/mL
(VEGF), standard curve range: 0.01-15 ng/mL
(KIM-1), standard curve range: 0.05-50 ng/mL
(β-2-Microglobulin), standard curve range: 0.005-5 ng/mL
(IP-10), standard curve range: 0.05-50 ng/mL
(Renin), sensitivity: 0.001-0.041 ng/mL
(MinDC+2SD), standard curve range: 0.02-25 ng/mL
(TIMP-1)

assay range

accuracy: 99.2-128.2%, sensitivity: 0.001-7.495 ng/mL, standard curve range: 0.001-0.5 ng/mL
(AGP), standard curve range: 0.005-4.0 ng/mL
(Adipsin), standard curve range: 0.014-10 ng/mL
(CRP), standard curve range: 0.549-400 ng/mL
(Haptoglobin), standard curve range: 13.717-10,000 ng/mL
(SAP), standard curve range: 6.858-5000 ng/mL
(A2M), inter-assay cv: <15%
intra-assay cv: <10%

assay range

accuracy: 62-90%, intra-assay cv: <10, sensitivity: 0.05-0.56 ng/mL
(MinDC+2SD), standard curve range: 0.05-50 ng/mL
(Lipocalin-2/NGAL), standard curve range: 0.05-50 ng/mL
(Uromodulin), standard curve range: 0.10-100 ng/mL
(TIMP-1), standard curve range: 0.20-200 ng/mL
(Osteoactivin), standard curve range: 0.24-250 ng/mL
(α-1-Microglobulin), standard curve range: 0.49-500 ng/mL
(Collagen IV)

assay range

accuracy: 77-92%, standard curve range: 12.2-50,000 pg/mL

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

General description

The MILLIPLEX® Mouse Kidney Injury Bead Panel 1 contains all the components necessary to measure the following six biomarkers in any combination using Luminex® xMAP® technology: β-2-Microglobulin, IP-10, KIM-1, Renin, TIMP-1, VEGF. The kit uses a 96-well format, contains a lyophilized standard cocktail, two quality controls and can measure up to 38 urine samples in duplicate.

Application

  • Analytes: β-2-Microglobulin, IP-10, KIM-1, Renin TIMP-1, VEGF
  • Recommended Sample type: urine
  • Recommended Sample dilution: 1:25
  • Assay Run Time: overnight
  • Research Category: Toxicity

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Other Notes

Please contact Technical Service for linearity of dilution.
Sensitivity: Please see kit protocol for individual assay sensitivities.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Questions

  1. What is the reason that B2M and VEGF are specified for urine only?

    1 answer
    1. In the process of developing the panel for serum and plasma, B2M and VEGF were found to be undetectable in the tested samples. As a result, these two components were excluded from the panel.

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