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MilliporeSigma

MMHE-44K

MILLIPLEX® Mouse Metabolic Hormone Expanded Panel

Configurable Mouse Metabolic Hormone Expanded 15-Plex Panel

Synonym(s):

diabetes and obesity assay overview, endocrine hormone multiplex kit, metabolic syndrome detection panel, mouse appetite regulation panel, mouse metabolic biomarker panel, mouse metabolic health assay, multiplex hormone profiling kit

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161503

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species reactivity

mouse

technique(s)

multiplexing: suitable

input

tissue/cellular lysate
culture supernatant(s)

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

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species reactivity

human

species reactivity

human

species reactivity

nonhuman primates

species reactivity

rat

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP®)

detection method

fluorometric (Luminex® xMAP®)

detection method

fluorometric (Luminex xMAP)

detection method

fluorometric (Luminex® xMAP®)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 15 analytes in mouse serum, plasma, or tissue/lysate and culture supernatant samples.

Analytes Included: Amylin (active), C-Peptide 2, Ghrelin (active), GIP (total), GLP-1 (active), GLP-1 (total), Glucagon, IL-6, Insulin, Leptin, MCP-1/CCL2, Pancreatic Polypeptide (PP), PYY (total), Resistin, Secretin, TNFα Note: GLP-1 Active and GLP-1 Total cannot be run together in the same assay.

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Targets key hormones involved in glucose regulation, appetite control, and inflammation
  • Includes 16 analytes relevant to metabolic syndrome, obesity, and diabetes research
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with mouse serum, plasma, and cell/tissue culture supernatants
  • Designed for research in metabolic disorders, endocrine function, and inflammatory pathways
Benefits:

  • Provides a comprehensive profile of metabolic and inflammatory hormones in mouse models
  • Supports investigation of insulin resistance, appetite regulation, and energy balance
  • Facilitates evaluation of therapeutic interventions in obesity, diabetes, and metabolic syndrome
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for preclinical and translational research

General description

Metabolic syndrome is characterized by a cluster of conditions including insulin resistance, obesity, dyslipidemia, and chronic inflammation. This panel—Amylin (active), C-Peptide 2, Ghrelin (active), GIP (total), GLP-1 (active), GLP-1 (total), Glucagon, IL-6, Insulin, Leptin, MCP-1/CCL2, Pancreatic Polypeptide (PP), PYY (total), Resistin, Secretin, and TNFα—captures key indicators of metabolic and inflammatory regulation. The MILLIPLEX® Mouse Metabolic Hormone Expanded Panel enables multiplexed quantification of these biomarkers in mouse serum or plasma, supporting research in obesity, diabetes, and metabolic disease.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

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Questions

  1. The protocol cites samples loaded can be at most 10uL neat, does this mean there is some capacity to dilute samples /load less than 10 uL and still be able to run the plate efficiently. If this is the case, what are the limits?

    1 answer

    1. Dilution may be required for some sample types, however the maximum volume of neat serum or plasma is 10 uL.

      Further details would be required to fully address your question. Please navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquiries" under the Products Section with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.

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