MX0HC10FS1

Millistak+^® HC Pro Pod Depth Filter

X0HC, cellulose, filtration area 1.1 m², hydrophilic

• Synonym(s): Millistak+ HC Pod Depth Filter, X0HC media series, 1.1 m ² surface area
• eCl@ss: 32031690

Properties

• material: cellulose ; filter aid (inorganic); glass fiber-reinforced polypropylene
• Quality Level: 400
• description: Secondary clarification of bioreactor harvests, primarily for cell cultures
• feature: hydrophilic
• manufacturer/tradename: Millistak+^®
• parameter: 1 bar max. differential pressure (15 psid) at 80 °C (Forward); 1 bar max. inlet pressure (15 psi) at 80 °C; 2.1 bar max. differential pressure (30 psid) at 25 °C (Forward); 2.1 bar max. differential pressure (30 psid) at 25 °C (Reverse); 3.5 bar max. inlet pressure (50 psi) at 25 °C
• H: 32 cm (12.5 in.)
• L: 62 cm (24.2 in.)
• filtration area: 1.1 m²
• impurities: <0.25 EU/mL bacterial endotoxins (LAL test, Aqueous extraction)
• input: sample type liquid
• conductivity: 19.34-53.2 μS/cm at 25 °C (product water)
• filter grade: X0HC

Description

General description

The Millistak+^® depth filter media is offered in a scalable, disposable format providing greater flexibility because of its unique modular design. The Millistak+^® MX0HC10FS1 comes in a POD format featuring a 32 cm (H) x 62 cm (L) and a filtration area of 1.1 m².

This X0HC media series delivers optimal performance through a gradient density matri, ideal for secondary clarification post depth filtration or centrifugation. Can also be utilized in downstream processing steps to protect chromatography columns. applications. Millistak+^® Pod filters are available in three distinct series of media grades in order to meet your specific needs - DE, CE and HC.

The Millistak+^® Pod system is ideal for a wide variety of primary and secondary clarification applications, including cell cultures, yeast and E. coli lysates post centrifuge, E. coli refolds, media, vaccines, plasma proteins and sera.

Easy to Use

With the compact, modular design of our Millistak+^® new Pod system, you can increase productivity and shorten cycle times.

Installation and setup of the Pod system is simple and straightforward. The unique design of the disposable adapters and disposable manifolds makes it easy to connect the Pod filters to rest of the unit operations in the process. The self-contained and disposable nature of the system protects operators from exposure to biohazards and eliminates maintenance as well as cleaning validation requirements.

Application

Secondary clarification of bioreactor harvests, primarily for cell cultures

Features and Benefits

• Low hold-up volume for greater product yield
• Broad range of media types offered in single and multilayer products
• Millistak+^® HC dual-action media improves prefiltration and compresses clarification
• Flexible, modular format offers scalability from 5 to 12,000 liters or more
• Patented disposable design eliminates need for housing, CIP or cleaning validation
• Self-contained Pod filters protect operators from exposure to biohazards
• Robust construction is easy to use and set up
• Smaller footprint facilitates use in tight spaces

Specifications

Filter Grade: X0HC

Per 24 hour soak in 10 L pure water post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 100 L/m² (10 L/ft² ) of media surface area:
Sodium: <14.1 mg/ft²
Calcium: <5.3 mg/ft²
Magnesium: <3.9 mg/ft²
Mercury: <0.001mg/ft²
Chromium: ≤0.001 mg/ft²
Aluminum: <0.084 mg/ft²
Potassium: <4.2mg/ft²
Lead: <0.001 mg/ft²
Arsenic: <0.009mg/ft²
Cobalt: ≤0.001 mg/ft²
Iron: <0.064 mg/ft²
Manganese: ≤ 0.124 mg/ft²
Titanium: <0.002 mg/ft²
Zinc: <0.046 mg/ft²
Nickel: <0.013
Copper: <0.009

Preparation Note

Sterilization Method
1 autoclave cycle of 60 min @ 123 ºC

Analysis Note

Product Water Conductivity at 25°C: post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 10 liters per ft² (100 L/m²) of media surface area

Legal Information

MILLISTAK+ is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable