MX0SP014H1

Millistak+^® HC Pro Pod Depth Filter

X0SP, filtration area 0.014 m², Lab Scale

• Synonym(s): Millistak+ Pro Pod Depth Filter, X0SP media series, 0.014 m ² surface area, 1/4 in. Hose Barb connection
• UNSPSC Code: 23151806
• eCl@ss: 32031690

Properties

• Product Name: Millistak+^® HC Pro Pod Depth Filter, X0SP, filtration area 0.014 m², hydrophilic
• material: acrylic ; polypropylene ; silica filter aid
• Quality Level: 400
• description: Secondary clarification of bioreactor harvests, post centrate harvest
• feature: hydrophilic
• manufacturer/tradename: Millistak+^®
• parameter: 2.1 bar max. differential pressure (30 psid) at 25 °C (Forward); 30 psid max. differential pressure (2.1 bar) at 37 °C (Reverse); 30 psid max. differential pressure (2.1 bar) at 4 °C (Forward); 30 psid max. inlet pressure (2.1 bar) at 25 °C
• H: 140 mm ; 5.5 in. (14 cm)
• L: 8.6 in. (22 cm)
• filtration area: 0.014 m²
• impurities: <0.25 EU/mL bacterial endotoxins (LAL test, Aqueous extraction)
• input: sample type liquid
• conductivity: 19.34-53.2 μS/cm at 25 °C (product water)
• filter grade: X0SP

Description

General description

The Millistak+^® Pod Depth Filter is a synthetic depth filter providing a cleaner and more consistent depth filtration media over current diatomaceous earth (DE) and cellulose (CE) based filter offerings. This unit, featured in a Lab Scale Pod format with a X0SP media grade, supports primary and secondary clarification as well as downstream filtration applications.

Application

Secondary clarification of bioreactor harvests, post centrate harvest

Features and Benefits

Synthetic materials of construction

• Reduce TOC extractables and pre-use flush volume requirements by 50%
• No beta glucans to interfere with limulous amoebocyte lysate (LAL) testing for bacterial endotoxins

Lot to lot consistency for successful development and implementation of robust clarification processes

Depth filter media formulation & design

• Provide as much as two times the filtration capacity with equivalent filter retention properties over commercial DE-based benchmarks
• Improved HCP impurity clearance

Disposable Pod device

• Flexible, modular format offers scalability from 5 to 12,000 liters or more
• Robust device format; easy to use and set up

Specifications

Filter Grade: X0SP

Trace metals were measured post pure water flush of 50 L/m² of surface area and 24-hour static soak in pure water. Values based on average of metals extractibles data from three separate uPod device lots. The analysis was made by ICP-MS. The devices were not autoclaved.

Preparation Note

Sterilization Method
1 autoclave cycle of 60 min @ 123 ºC, filtration performance may be impacted. Recommended for post use contamination only.

Analysis Note

Product Water Conductivity at 25°C: post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 10 liters per ft² (100 L/m²) of media surface area

Legal Information

MILLISTAK+ is a registered trademark of Merck KGaA, Darmstadt, Germany