P2B500V01

Pellicon^® 2 Mini Cassette Media: Biomax^® 500 kDa

Chemistry: Polyethersulfone (PES) Screen Type: V Device Size: 0.1 m²

• Synonym(s): Pellicon^® 2 Mini Ultrafiltration Module Biomax-500 V 0.1 m², Pellicon^® 2 Mini Ultrafiltration Biomax^® Module
• UNSPSC Code: 23151806

Properties

• Product Name: Pellicon^® 2 Mini Cassette Media: Biomax^® 500 kDa, Chemistry: Polyethersulfone (PES) Screen Type: V Device Size: 0.1 m²
• Quality Level: 400
• material: polyethersulfone , polypropylene screen, polyurethane adhesive
• manufacturer/tradename: Pellicon^®
• parameter: 0.33 bar max. transmembrane pressure (5 psig) (reverse), 5-35 L/min recirculation rate at 0.4 bar (6 psi), 7 bar max. transmembrane pressure (100 psig) at 30 °C (forward)
• technique(s): analytical sample preparation: suitable, protein purification: suitable
• H: 2.16 cm (0.85 in.)
• L: 21 cm (8.3 in.)
• W: 5.6 cm (2.2 in.)
• filtration area: 0.1 m²
• membrane nominal area: 0.1 m²
• gravimetric extractables: ≤1500 mg/m²
• matrix: Biomax^®
• pore size: 500 kDa NMWCO
• pH: 1-14

Description

General description

The Pellicon^® 2 Ultrafiltration BIOMAX 500 Mini Cassette sets the standard in cassette-style tangential flow filtration devices. P2B500V01 was designed with process scale-up and applications development in mind.

Millipore′s BIOMAX 500 polyethersulfone membrane has void-free structures that guard against leakage of solutes through microdefects normally associated with voids beneath the thin skins of conventional UF membranes. These void-free membranes are more permeable, resulting in high-flux with equivalent or superior product retention. These void-free membranes provide the advantages of fast, high yield processing and smaller systems.

The Pellicon^® 2 Mini Ultrafiltration BIOMAX Module feature a filtration area of 0.1 m² with a pore size of 500 kDa NMWCO.

Application

Concentration, desalting or buffer exchange of:

• Protein solutions
• Polysaccharide solutions
• Virus suspensions

Harvest, washing or clarification of:

• Cell cultures and lysates
• Colloidal suspensions
• Viral cultures

Features and Benefits

• Type V screen (open channel)
• Leading-edge void- free membranes to match virtually any separation challenge
• Short flow path for higher flux and higher resolution separation capability
• Choice of flow channel configuration providing process optimization capability
• Predictable, fast, scale-up
• True linear scalability from laboratory size modules to industrial assemblies for processing thousands of liters
• Brings higher resolution, improved yields and superior back-pressure resistance
• Ultracel membranes are composite membranes cast on a microporous substrate for defect-free membranes with superior

Analysis Note

Gravimetric Extractables: after a water flush

Other Notes

Prefiltration Rquirements: 100 µm

These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.

Legal Information

BIOMAX is a registered trademark of Merck KGaA, Darmstadt, Germany

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 2