The multi-species cross-reactivity data for the Rat Liver Injury Panel is attached. Please note that this is based on 4 samples from each species and standards were not tested to determine the amount of cross-reactivity. For samples below detection, the lack of signal may not necessarily indicate an absence of cross-reactivity and could be due to low levels in the few samples tested.
RLI1MAG-92K
MILLIPLEX® Rat Liver Injury Panel
Configurable Rat Liver Injury 5-Plex Panel
Synonym(s):
liver injury biomarker panel for rats, rat drug safety liver panel, rat hepatotoxicity multiplex assay, rat liver enzyme panel, rat liver function assay
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
To order a Milliplex® kit, please search for your analyte of interest.
Product Name
MILLIPLEX® Rat Liver Injury Panel,
Quality Level
species reactivity
rat
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
accuracy: 77-92%, sensitivity: 0.021-4.038 ng/mL
(MinDC+2SD), standard curve range: 0.02-15.0 ng/mL
(GSTα), standard curve range: 0.04-30.0 ng/mL
(5′-NT/CD73), standard curve range: 0.08-60.0 ng/mL
(GOT1), standard curve range: 0.10-75.0 ng/mL
(ARG1), standard curve range: 0.62-450.0 ng/mL
(SDH)
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
5′NT/CD73 and ARG1 are markers of liver function and metabolic activity. GOT1 and SDH are enzymes released during hepatocellular injury, while GSTα reflects oxidative stress and detoxification. Together, these biomarkers provide a comprehensive view of liver damage and function in rat models.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 5 analytes rat serum or plasma samples.
Analytes Included: 5′NT/CD73, ARG1, GOT1, GSTα, SDH
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy
Analytes Included: 5′NT/CD73, ARG1, GOT1, GSTα, SDH
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy
Features and Benefits
Features:
- Multiplex detection of 5 liver injury biomarkers in one assay
- Magnetic bead-based format for efficient and reproducible processing
- Compatible with rat serum, plasma, and tissue lysates
- High sensitivity for early detection of hepatocellular damage
- Conserves sample volume and reagents through multiplexing
- Improves data quality and reproducibility with magnetic bead format
- Enables early detection and monitoring of liver injury
- Supports translational research in liver disease and toxicology
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
1 of 1
This Item | |||
|---|---|---|---|
| species reactivity rat | species reactivity rat | species reactivity rat | species reactivity rat |
| manufacturer/tradename Milliplex® | manufacturer/tradename Milliplex® | manufacturer/tradename Milliplex® | manufacturer/tradename Milliplex® |
| assay range accuracy: 77-92%, standard curve range: 0.02-15.0 ng/mL | assay range accuracy: 97-108%, intra-assay cv: <10%, standard curve range: 0.1-100 ng/mL | assay range accuracy: 80-131%, standard curve range: 0.2-1,000 pg/mL | assay range accuracy: 67-92%, standard curve range: 0.1-40 ng/mL |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| detection method fluorometric (Luminex xMAP) | detection method fluorometric (Luminex® xMAP® technology) | detection method fluorometric (Luminex® xMAP® technology) | detection method fluorometric (Luminex® xMAP® technology) |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
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Related Content
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Clinical and experimental reproductive medicine, 48(2), 124-131 (2021-05-25)
Approximately 30% of preeclamptic pregnancies exhibit abnormal liver function tests. We assessed liver injury-associated enzyme levels and circulating transforming growth factor beta (TGF-β) levels in an arginine vasopressin (AVP)-induced pregnant Sprague-Dawley rat model. Pregnant and non-pregnant Sprague-Dawley rats (n=24) received
Global Trade Item Number
| SKU | GTIN |
|---|---|
| RLI1MAG-92K | 04055977130737 |
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Is the Rat Liver Injury Panel (RLI1MAG-92K) kit cross-reactive to mouse or other mammalian species?
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