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SKBM04760

Millipore

Strat-M® Membrane, Transdermal Diffusion Test Model, 47mm

Strat-M membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety & storage limitations.

eCl@ss:
32160907
NACRES:
NB.24
Pricing and availability is not currently available.

material

plain filter
polyethersulfone membrane (synthetic lipid post-treatment)
polyolefin membrane (synthetic lipid post-treatment)
white filter

Quality Level

sterility

non-sterile

mfr. no.

Millipore
Strat-M®

diam.

4.7 cm

thickness

300 μm

shipped in

ambient

General description

Strat-M Membrane for Transdermal Diffusion Testing
Experience the unmatched predictability of Strat-M membrane – a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

Strat-M membrane is designed for screening of:
•Active pharmaceutical ingredients (API)
•Cosmetic actives
•Formulations
•Personal care products
•Pesticides and chemicals

Human Skin Correlation
Strat-M membrane is predictive of diffusion in human skin for a wide range of compounds and formulations. Use the Compound Correlation Tool to learn how well Strat-M membrane will work for you.

Reproducible Diffusion Data:
No need to repeat testing each time a new lot of skin arrives in the lab. Strat-M membrane is a highly consistent, engineered material that allows you to compare today’s diffusion data with data you will generate next week, or next month. Furthermore, lot-to-lot consistency brings a new level of clarity to your test data, simplifying your analysis.

Sensitive to Enhancers
Strat-M membrane exhibits differential permeability in the presence of enhancers and is compatible with common formulation formats, so it is appropriate for use during formulation optimization.

Ultimate Experimental Convenience
Strat-M membrane was designed with convenience in mind. The Strat-M membrane is shelf-stable and stocked in the warehouse so procurement and storage is a breeze. Each membrane is individually packaged as precut discs and do not need to be hydrated prior to use. Simply remove the Strat-M membrane disc from its pouch and load into a Franz cell.

Legal Information

STRAT-M is a registered trademark of Merck KGaA, Darmstadt, Germany
Certificate of Analysis
Certificate of Origin
CURCUMIN-EUDRAGIT? E PO SOLID DISPERSION: A SIMPLE AND POTENT METHOD TO SOLVE THE PROBLEMS OF CURCUMIN.
Li J, Lee IW, Shin GH, Chen X, Park HJ.
European Journal of Pharmaceutics and Biopharmaceutics null
PREPARATION OF A CAPSAICIN-LOADED NANOEMULSION FOR IMPROVING SKIN PENETRATION
Kim JH, Ko JA, Kim JT, Cha DS, Cho JH, Park HJ, Shin GH.
Journal of Agricultural and Food Chemistry null
PREDICTION OF SKIN PERMEATION BY CHEMICAL COMPOUNDS USING THE ARTIFICIAL MEMBRANE, STRAT-M?
Uchida T, Kadhum WR, Kanai S, Todo H, Oshizaka T, Sugibayashi K
European Journal of Pharmaceutical Sciences null
A REVIEW OF THE CURRENT STATE OF THE ART OF PHYSIOLOGICALLY-BASED TESTS FOR MEASURING HUMAN DERMAL IN VITRO BIOAVAILABILITY OF POLYCYCLIC AROMATIC HYDROCARBONS (PAH) IN SOIL
Beriro DJ, Cave MR, Wragg J, Thomas R, Wills G, Evans F.
Journal of Hazardous Materials null
IN VITRO SKIN MODELS AS A TOOL IN OPTIMIZATION OF DRUG FORMULATION.
Flaten GE, Palac Z, Engesland A, Filipovic-Grcic J, Vanic Z, Skalko-Basnet N
European Journal of Pharmaceutical Sciences null
Articles
Understand how a Strat-M synthetic membrane model can be an alternative to human or animal skin when screening for effectiveness of encapsulation on reducing transdermal diffusion of skin care actives
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