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11074440001

Roche

Penicillin-Streptomycin

suitable for cell culture, lyophilized (clear, colorless solution after reconstitution), non-sterile; 0.2 μm filtered, sufficient for 20 mL

Synonym(s):
antibiotic

Quality Level

sterility

non-sterile; 0.2 μm filtered

form

lyophilized (clear, colorless solution after reconstitution)

usage

sufficient for 20 mL

manufacturer/tradename

Roche

concentration

50 mg/mL streptomycin in 0.9% NaCl (as sulfate)
50,000 U/mL penicillin in 0.9% NaCl

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes
protein synthesis | interferes

shipped in

wet ice

storage temp.

2-8°C

General description

Penicillin (Penicillin G) inhibits bacterial growth by inhibiting peptidoglycan synthesis. Streptomycin belongs to the family of aminoglycoside antibiotics and inhibits bacterial growth by inhibiting protein synthesis.
Penicillin (Penicillin G) inhibits bacterial growth by inhibiting peptidoglycan synthesis. Streptomycin belongs to the family of aminoglycoside antibiotics, and inhibits bacterial growth by inhibiting protein synthesis. Penicillin-Streptomycin is used for the prevention and elimination of bacterial contaminants in cell culture.
Penicillin G, sodium salt; streptomycin sulfate
Sensitive organisms:
  • Gram-positive bacteria (penicillin)
  • Gram-negative bacteria (streptomycin)
  • Stability:Penicillin: 3 days
  • Streptomycin: 3 days in media at +37 °C
Cytotoxic concentration: 10,000 IU/ml penicillin, 20 mg/ml streptomycin

Application

Penicillin-Streptomycin has been used for the prevention and elimination of bacterial contaminants in cell culture.

Physical form

Lyophilizate, 50,000 U/ml penicillin G and 50 mg/ml streptomycin (as sulfate) in 0.9% NaCl

Preparation Note

Working concentration: 100 IU/ml penicillin
100 μg/ml streptomycin

Reconstitution

Dissolve in 20mL distilled water.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Disease relevant modifications of the methylome and transcriptome by particulate matter (PM2.5) from biomass combustion
He?elbach K, et al.
Epigenetics, 1-14 (2017)
Lysozyme and penicillin inhibit the growth of anaerobic ammonium-oxidizing planctomycetes.
Hu Z, et al.
Applied and Environmental Microbiology, 79(24), 7763-7769 (2013)
Ali Can Sahillioglu et al.
Cancer immunology research, 9(9), 999-1007 (2021-07-02)
Adoptive transfer of genetically modified or donor-derived T cells can efficiently eradicate human tumors but is also frequently associated with major toxicity. There are several switches that can be used to kill the infused cell pool in the case of
Matteo Zurlo et al.
International journal of oncology, 59(2) (2021-07-20)
In the development of novel and more effective anticancer approaches, combined treatments appear to be of great interest, based on the possibility of obtaining relevant biological or therapeutic effects using lower concentrations of single drugs. Combination therapy may prove to
Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma
Hooijkaas A, et al.
Oncoimmunology, 1(5), 609-617 (2012)

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