International journal of pharmaceutics, 386(1-2), 108-113 (2009-11-20)
This work evaluates the effect of different bicellar systems on the percutaneous absorption of diclofenac diethylamine (DDEA) using two different approaches. In the first case, the drug was included in bicellar systems, which were applied on the skin and, in
Journal of chromatography. A, 1307, 66-72 (2013-08-15)
The extraction efficiency of analytes in a cold fiber headspace solid-phase microextraction (CF-HS-SPME) system was investigated both theoretically and experimentally. The system was applied for quantitative extraction of polycyclic aromatic hydrocarbons (PAHs) from solid matrices. In order to achieve better
The journal of physical chemistry. A, 112(40), 9742-9750 (2008-09-16)
Five aryliminopropadienones 4a- d have been synthesized by flash vacuum thermolysis (FVT) by using two different precursors in each case. These compounds were deposited at 50 K at a pressure of ca. 10(-6) mbar together with three different nucleophiles, namely
Journal of chromatography. A, 1216(44), 7450-7455 (2009-06-26)
A polysaccharide-based chiral stationary phase (Sepapak-4), with cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral selector, has been investigated in liquid chromatography (LC). Its enantioresolution power was evaluated towards 13 basic amino-drugs with widely different structures and polarities, using polar organic mobile phases. After
Second-order rate constants of the diethylamine-promoted enantiomerization of 2-[2-(1-methyl-1H-pyrrol-2-yl)-2-oxo-1-phenylethyl]-isoindole-1,3-dione, a chiral alpha-substituted ketone endowed with high anti-MAO activity type-A, were measured by dynamic high-performance liquid chromatography (DHPLC), stopped-flow high-performance liquid chromatography (sf-HPLC), and a classical method based on enantioselective HPLC
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
