19-2190

L-Methionine

Name: <SC>L</SC>-Methionine
Brand: SAJ

SAJ special grade, ≥98.5%

Synonym(s):

(S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid

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About This Item

Linear Formula:

CH₃SCH₂CH₂CH(NH₂)CO₂H

CAS Number:

63-68-3

Molecular Weight:

149.21

EC Number:

200-562-9

UNSPSC Code:

12352112

PubChem Substance ID:

329751692

Beilstein/REAXYS Number:

1722294

MDL number:

MFCD00063097

Assay:

≥98.5%

Grade:

SAJ special grade

Key Documents

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InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

SMILES string

CSCC[C@H](N)C(O)=O

grade

SAJ special grade

assay

≥98.5%

form

solid

availability

available only in Japan

dilution

(for analytical testing)

mp

284 °C (dec.) (lit.)

application(s)

peptide synthesis

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Show Differences

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This Item	M5308	PHR1241	64319
Sigma-Aldrich 19-2190 L-Methionine	Sigma-Aldrich M5308 L-Methionine	Supelco PHR1241 L-Methionine	Sigma-Aldrich 64319 L-Methionine
application(s) peptide synthesis	application(s) peptide synthesis pharmaceutical (small molecule)	application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care pharmaceutical (small molecule)	application(s) -
grade SAJ special grade	grade -	grade certified reference material, pharmaceutical secondary standard	grade -
assay ≥98.5%	assay 99.0-101.0%	assay -	assay ≥99.5% (NT)
form solid	form powder	form -	form powder or crystals
mp 284 °C (dec.) (lit.)	mp 284 °C (dec.) (lit.)	mp 284 °C (dec.) (lit.)	mp 284 °C (dec.) (lit.)
availability available only in Japan	availability -	availability -	availability -

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans.

Ronald O Ball et al.

The Journal of nutrition, 136(6 Suppl), 1682S-1693S (2006-05-17)

Sulfur amino acid metabolism has been receiving increased attention because of the link to chronic diseases such as cardiovascular disease, Alzheimer's disease, and diabetes. In addition, the role of cysteine and optimal intakes for physiological substrates such as glutathione are

Fragmentation reactions of methionine-containing protonated octapeptides and fragment ions therefrom: an energy-resolved study.

Alex G Harrison

Journal of the American Society for Mass Spectrometry, 24(10), 1555-1564 (2013-08-15)

The fragmentation reactions of the MH(+) ions as well as the b7, a7, and a7* ions derived therefrom have been studied in detail for the octapeptides MAAAAAAA, AAMAAAAA, AAAAMAAA, and AAAAAAMA. Ionization was by electrospray using a QqToF mass spectrometer

Value of 11C-methionine PET in imaging brain tumours and metastases.

Andor W J M Glaudemans et al.

European journal of nuclear medicine and molecular imaging, 40(4), 615-635 (2012-12-13)

(11)C-methionine (MET) is the most popular amino acid tracer used in PET imaging of brain tumours. Because of its characteristics, MET PET provides a high detection rate of brain tumours and good lesion delineation. This review focuses on the role

Planar scintigraphy with 123I/99mTc-sestamibi, 99mTc-sestamibi SPECT/CT, 11C-methionine PET/CT, or selective venous sampling before reoperation of primary hyperparathyroidism?

Camilla Schalin-Jäntti et al.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(5), 739-747 (2013-04-05)

All patients with primary hyperparathyroidism should undergo localization studies before reoperation, but it is not known which method is most accurate. The purpose of this prospective study was to compare the performance of planar scintigraphy with (123)I/(99m)Tc-sestamibi, (99m)Tc-sestamibi SPECT (SPECT/CT)

Correction of the consequences of mitochondrial 3243A>G mutation in the MT-TL1 gene causing the MELAS syndrome by tRNA import into mitochondria.

Olga Z Karicheva et al.

Nucleic acids research, 39(18), 8173-8186 (2011-07-05)

Mutations in human mitochondrial DNA are often associated with incurable human neuromuscular diseases. Among these mutations, an important number have been identified in tRNA genes, including 29 in the gene MT-TL1 coding for the tRNA(Leu(UUR)). The m.3243A>G mutation was described

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