30-5000

Tris Base

Name: Tris Base
Brand: SAJ

≥99.0%, solid, JIS special grade

Synonym(s):

Tris Base, Tris(hydroxymethyl)aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol

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About This Item

Linear Formula:

NH₂C(CH₂OH)₃

CAS Number:

77-86-1

Molecular Weight:

121.14

Beilstein/REAXYS Number:

741883

MDL number:

MFCD00004679

UNSPSC Code:

12352116

PubChem Substance ID:

329753524

Grade:

JIS special grade

Assay:

≥99.0%

Bp:

219-220 °C/10 mmHg (lit.)

Key Documents

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Product Name

Tris(hydroxymethyl)aminomethane, JIS special grade, ≥99.0%

grade

JIS special grade

assay

≥99.0%

form

solid

availability

available only in Japan

dilution

(for analytical testing)

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)

mp

167-172 °C (lit.)

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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Chemistry & Biochemicals

Tris

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Show Differences

1 of 4

This Item	252859	30-5025	1.08382
Sigma-Aldrich 30-5000 Tris(hydroxymethyl)aminomethane	Sigma-Aldrich 252859 Tris(hydroxymethyl)aminomethane	Sigma-Aldrich 30-5025 Tris(hydroxymethyl)aminomethane	Millipore 1.08382 Tris(hydroxymethyl)aminomethane
grade JIS special grade	grade ACS reagent	grade -	grade ACS reagent
assay ≥99.0%	assay ≥99.8%, 99.8-100.1%	assay ≥99.8%	assay -
form solid	form crystalline	form solid	form solid
mp 167-172 °C (lit.)	mp 167-172 °C (lit.)	mp 167-172 °C (lit.)	mp 167-172 °C (lit.)
bp 219-220 °C/10 mmHg (lit.)	bp 219-220 °C/10 mmHg (lit.)	bp 219-220 °C/10 mmHg (lit.)	bp 219-220 °C/10 mmHg (lit.), 219-220 °C/13.3 hPa
availability available only in Japan	availability -	availability available only in Japan	availability -

Application

Composition of the Sheath of Sphaerotilus Natans.: This study analyzes the sheath structure of Sphaerotilus natans, potentially utilizing Tris(hydroxymethyl)aminomethane in the process, to explore its biochemical and microbiological aspects (Romano et al., 1963).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Acquisition strategy to reduce cerebrospinal fluid partial volume effects for improved DTI tractography.

Corey A Baron et al.

Magnetic resonance in medicine, 73(3), 1075-1084 (2014-04-12)

An acquisition method that does not increase scan time or specific absorption rate is investigated for reducing the deleterious effects of cerebrospinal fluid (CSF) partial volume effects on diffusion tensor imaging (DTI) tractography. It is based on using a shorter

Magnetic nanoparticles to recover cellular organelles and study the time resolved nanoparticle-cell interactome throughout uptake.

Filippo Bertoli et al.

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Nanoparticles in contact with cells and living organisms generate quite novel interactions at the interface between the nanoparticle surface and the surrounding biological environment. However, a detailed time resolved molecular level description of the evolving interactions as nanoparticles are internalized

Clinical pharmacokinetics of ketorolac tromethamine.

D R Brocks et al.

Clinical pharmacokinetics, 23(6), 415-427 (1992-12-01)

Ketorolac is a new chiral nonsteroidal anti-inflammatory drug (NSAID) which is marketed for analgesia as the racemate. The drug is administered as the water soluble tromethamine salt and is available in tablets or as an intramuscular injection. The absorption of

A rhenium tris-carbonyl derivative as a single core multimodal probe for imaging (SCoMPI) combining infrared and luminescent properties.

Sylvain Clède et al.

Chemical communications (Cambridge, England), 48(62), 7729-7731 (2012-06-29)

A rhenium tris-carbonyl derivative has been designed to couple infrared and luminescent detection in cells. Both spectroscopies are consistent with one another; they point out the reliability of the present SCoMPI (for Single Core Multimodal Probe for Imaging) for bimodal

Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo.

Noelia Purroy et al.

Oncotarget, 6(10), 7632-7643 (2014-12-30)

Chronic lymphocytic leukemia (CLL) cells residing in the bone marrow (BM) and in secondary lymphoid tissues receive survival and proliferative signals from the microenvironment, resulting in persistence of residual disease after treatment. In this study, we characterized primary CLL cells

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