00942

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

for GC derivatization, LiChropur^™, ≥95.0% (GC), with 1% tert-Butyldimethylchlorosilane

• Synonym(s): N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, MTBSTFA + 1% TBDMSCl, Silylating mixture VI
• Empirical Formula (Hill Notation): C₉H₁₈F₃NOSi
• CAS Number: 77377-52-7
• Molecular Weight: 241.33
• Beilstein/REAXYS Number: 3606546
• MDL number: MFCD00009671
• UNSPSC Code: 41116105
• PubChem Substance ID: 329747171
• NACRES: NA.22

Properties

• Product Name: N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane, LiChropur^™, ≥95.0% (GC)
• grade: derivatization grade ((GC derivatization))
• Quality Level: 100
• assay: ≥95.0% (GC)
• form: liquid
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Silylations
• technique(s): gas chromatography (GC): suitable
• impurities: 0.5-1.5% tert-butyldimethylchlorosilane
• storage temp.: 2-8°C
• SMILES string: CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C
• InChI: 1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3
• InChI key: QRKUHYFDBWGLHJ-UHFFFAOYSA-N

Description

General description

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamidewith 1% tert-Butyldimethylchlorosilane (TBDMS) is a derivatizing reagentcommonly used in gas chromatography (GC) and gas chromatography-massspectrometry (GC-MS).[1]

Application

MTBSTFA + 1% TBDMSCl can be used as a derivatizing reagentin the analysis of:

• Organic acid profile in human serum by gaschromatography/mass spectrometry (GC/MS).[1]
• Nerveagents and their breakdown products by GC–MS-MS method.[2]

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS07
• signalword: Warning
• hcodes: H226,H315,H319
• pcodes: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 113.0 °F - closed cup
• flash_point_c: 45 °C - closed cup