03738

5-Fluorouracil

analytical standard

• Synonym(s): 2,4-Dihydroxy-5-fluoropyrimidine, 5-FU, 5-Fluoro-2,4(1H,3H)-pyrimidinedione
• Empirical Formula (Hill Notation): C₄H₃FN₂O₂
• CAS Number: 51-21-8
• Molecular Weight: 130.08
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329747789
• EC Number: 200-085-6
• Beilstein/REAXYS Number: 127172
• MDL number: MFCD00006018

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥99.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• impurities: ≤0.5% water
• mp: 282-286 °C (dec.) (lit.)
• application(s): cleaning products; cosmetics; food and beverages; forensics and toxicology; personal care; pharmaceutical (small molecule)
• format: neat
• SMILES string: FC1=CNC(=O)NC1=O
• InChI: 1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
• InChI key: GHASVSINZRGABV-UHFFFAOYSA-N
• Gene Information: human ... TYMS(7298)

Description

General description

5-Fluorouracil is an anti-tumor agent, widely used in the treatment of various malignancies.

Application

5-Fluorouracil may be used as an analytical standard for the determination of the analyte in hospital effluents by capillary electrophoresis,[1] and in biological samples[2][3] and environmental samples[4] by chromatography based techniques.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H351
• pcodes: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3