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03880590

Luteolin

primary reference standard

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Synonym(s):
3′,4′,5,7-Tetrahydroxyflavone
Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
491-70-3
Molecular Weight:
286.24
Beilstein:
292084
EC Number:
207-741-0
MDL number:
MFCD00017309
PubChem Substance ID:
329747828
NACRES:
NA.24

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

mp

~330 °C (lit.)

application(s)

food and beverages

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

InChI key

IQPNAANSBPBGFQ-UHFFFAOYSA-N

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This Item
PHL89245L928372511
Luteolin primary reference standard

03880590

Luteolin

Luteolin phyproof® Reference Substance

PHL89245

Luteolin

Luteolin ≥98% (TLC), powder

Sigma-Aldrich

L9283

Luteolin

Luteolin analytical standard

Supelco

72511

Luteolin

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

manufacturer/tradename

PhytoLab

manufacturer/tradename

-

manufacturer/tradename

-

mp

~330 °C (lit.)

mp

~330 °C (lit.)

mp

~330 °C (lit.)

mp

~330 °C (lit.)

application(s)

food and beverages

application(s)

-

application(s)

-

application(s)

food and beverages

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Luteolin 7-O-β-D-glucoside ≥98.0% (HPLC)

Sigma-Aldrich

74284

Luteolin 7-O-β-D-glucoside

Apigenin ≥97% (TLC), from citrus

Sigma-Aldrich

SMB00702

Apigenin

Apigenin 7-glucoside primary reference standard

00720585

Apigenin 7-glucoside

Kaempferol United States Pharmacopeia (USP) Reference Standard

USP

1354900

Kaempferol

Diosmetin

Sigma-Aldrich

D7321

Diosmetin

Kaempferol analytical standard

Supelco

96353

Kaempferol

Citric acid anhydrous for synthesis

Sigma-Aldrich

8.18707

Citric acid

Theoharis C Theoharides et al.
Advances in experimental medicine and biology, 601, 423-430 (2007-08-24)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) mainly mediated by Th1, but recent evidence indicates that Th2 T cells, mostly associated with allergic reactions, are also involved. Mast cells are involved in allergic and
Yong Lin et al.
Current cancer drug targets, 8(7), 634-646 (2008-11-11)
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and
Sung Wook Park et al.
Investigative ophthalmology & visual science, 53(12), 7718-7726 (2012-10-27)
Oxidative stress-induced vascular endothelial growth factor (VEGF) is thought to play a critical role in the pathogenesis of retinopathy of prematurity (ROP). This study was performed to investigate the anti-angiogenic effect of luteolin against reactive oxygen species (ROS)-induced retinal neovascularization.
Günter Seelinger et al.
Planta medica, 74(14), 1667-1677 (2008-10-22)
Luteolin is a flavone which occurs in medicinal plants as well as in some vegetables and spices. It is a natural anti-oxidant with less pro-oxidant potential than the flavonol quercetin, the best studied flavonoid, but apparently with a better safety
Leticia Correa Manjolin et al.
Food chemistry, 141(3), 2253-2262 (2013-07-23)
Fisetin, quercetin, luteolin and 7,8-hydroxyflavone show high activity in Leishmania cultures and present low toxicity to mammalian cells. In this work, the structural aspects of 13 flavonoids were analyzed for their inhibition of the arginase enzyme from Leishmania (Leishmania) amazonensis.
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