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03970590

Epigallocatechin gallate

primary reference standard

Synonym(s):

(−)-Epigallocatechin gallate, (−)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate, (−)-cis-3,3′,4′,5,5′,7-Hexahydroxy-flavane-3-gallate, EGCG

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10 MG

$418.00

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About This Item

Empirical Formula (Hill Notation):
C22H18O11
CAS Number:
989-51-5
Molecular Weight:
458.37
NACRES:
NA.24
PubChem Substance ID:
329747849
UNSPSC Code:
85151701
MDL number:
MFCD00075940

Key Documents

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InChI

1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1

SMILES string

Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4

InChI key

WMBWREPUVVBILR-WIYYLYMNSA-N

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

application(s)

food and beverages

storage temp.

−20°C

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1 of 4

This Item
PHR1333PHL896561236700
Epigallocatechin gallate primary reference standard

03970590

Epigallocatechin gallate

Epigallocatechin gallate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1333

Epigallocatechin gallate

(−)-Epigallocatechin 3-gallate phyproof® Reference Substance

PHL89656

(−)-Epigallocatechin 3-gallate

(−)-Epigallocatechin-3-O-gallate United States Pharmacopeia (USP) Reference Standard

USP

1236700

(−)-Epigallocatechin-3-O-gallate

grade

primary reference standard

grade

certified reference material, pharmaceutical secondary standard

grade

primary reference standard

grade

pharmaceutical primary standard

application(s)

food and beverages

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

manufacturer/tradename

HWI

manufacturer/tradename

-

manufacturer/tradename

PhytoLab

manufacturer/tradename

USP

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HWI03035-1
HWI03035
HWI02101-3
HWI02101-2
HWI02101-1

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Masaki Kanadzu et al.
Cancer letters, 241(2), 250-255 (2005-11-24)
(-)-Epigallocatechin gallate (EGCG), a catechin polyphenol component, is the main ingredient of green tea extract. Recently, increasing attention has been given to its anti-oxidant effects. However, several studies reported the oxidative effects of EGCG, suggesting that EGCG had a dual
Xiaofeng Meng et al.
Chemical research in toxicology, 15(8), 1042-1050 (2002-08-20)
(-)-Epigallocatechin gallate (EGCG), the most abundant tea catechin, has been proposed to be beneficial to human health based on its strong antioxidative and other biological activities in vitro. Inadequate knowledge regarding the bioavailability and biotransformation of EGCG in humans, however
M Ichihashi et al.
Journal of dermatological science, 23 Suppl 1, S45-S50 (2000-04-15)
Reactive oxygen species (ROS) have been shown to be responsible for inducing DNA damage after ultraviolet radiation (UV). Antioxidant, vitamin E and epigallocatechin gallate extracted from green tea, applied topically to the skin, delayed the onset of UV-induced skin cancer
Olivier M Dorchies et al.
American journal of physiology. Cell physiology, 290(2), C616-C625 (2006-01-13)
Duchenne muscular dystrophy is a frequent muscular disorder caused by mutations in the gene encoding dystrophin, a cytoskeletal protein that contributes to the stabilization of muscle fiber membrane during muscle activity. Affected individuals show progressive muscle wasting that generally causes
Silvia A Mandel et al.
Journal of Alzheimer's disease : JAD, 15(2), 211-222 (2008-10-28)
Although much progress has been made in understanding the pathogenesis of Alzheimer's disease (AD), the current therapeutic approaches are merely symptomatic, intended for the treatment of cognitive symptoms, such as disturbances in memory and perception. Novel promising strategies suggest the
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