04609

Supelco

O-Succinyl-L-carnitine lithium salt

≥98.0% (TLC)

Empirical Formula (Hill Notation):
C11H19NO6 · xLi+
Molecular Weight:
261.27 (free acid basis)
NACRES:
NA.24

Quality Level

assay

≥98.0% (TLC)

optical activity

[α]/D -16.0±3.0°, c = 0.1 in H2O

format

neat

storage temp.

2-8°C

Biochem/physiol Actions

O-Succinyl-L-carnitine (C4DC) is a secondary metabolite that is not directly involved in the normal growth, development or reproduction of an organism.arises from. O-Succinyl-L-carnitine arises from the TCA cycle intermediate succinyl-CoA in plasma and liver. It is an O-acylcarnitine having succinyl as the acyl substituent. O-Succinyl-L-carnitine is used as biomarker for inborn metabolic deseases related to succinyl-CoA synthase function.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Succinyl-CoA:acetoacetate transferase deficiency: identification of a new patient with a neonatal onset and review of the literature.
Niezen-Koning, K.E., et al.
The Journal of Pediatrics, 156, 870-873 (1997)
Cristiano Rizzo et al.
Clinica chimica acta; international journal of clinical chemistry, 429, 30-33 (2013-11-26)
Methylmalonic aciduria (MMA) is one of the most frequent organic acidurias, a class of diseases caused by enzymatic defects mainly involved in the catabolism of branched-chain amino acids. Recently, mild MMA and C4-dicarboxylyl-carnitine (C4DC-C) accumulation have been reported in patients...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.