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04642

Supelco

3-Acetylpyridine

analytical standard

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Synonym(s):
Methyl 3-pyridyl ketone
Empirical Formula (Hill Notation):
C7H7NO
CAS Number:
350-03-8
Molecular Weight:
121.14
Beilstein:
107751
EC Number:
206-496-7
MDL number:
MFCD00006396
PubChem Substance ID:
329747965
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥99.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.534 (lit.)
n20/D 1.535

bp

220 °C (lit.)

mp

11-13 °C (lit.)

density

1.102 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

CC(=O)c1cccnc1

InChI

1S/C7H7NO/c1-6(9)7-3-2-4-8-5-7/h2-5H,1H3

InChI key

WEGYGNROSJDEIW-UHFFFAOYSA-N

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Caution

may discolor to deep yellow on storage

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Ai-Li Cai et al.
The European journal of neuroscience, 24(8), 2169-2176 (2006-10-18)
Zinc neurotoxicity has been demonstrated in ischemic, seizure, hypoglycemic, and trauma-induced neuronal death where Zn(2+) is thought to be synaptically released and taken up in neighbouring neurons, reaching toxic concentrations. We previously demonstrated that toxicity of extracellular Zn(2+) depended on
T M Kuchmerovskaia et al.
Voprosy meditsinskoi khimii, 48(3), 264-270 (2002-09-24)
The effect of administration of 3-acetylpyridine (antivitamin B3), on rat brain serotoninergic and NAD receptor systems was investigated. The injection of 3-acetylpyridine to rats caused a decrease of NAD and serotonin content in the brain and changes in [U-14C]NAD binding
Sheldon J Moss et al.
Neuroscience letters, 321(1-2), 53-56 (2002-03-02)
There are no published reports assessing whether the non-immunosuppressant immunophilin ligand GPI-1046, which has putative neurotrophic effects in a variety of models of neurotoxicity, possesses neuroprotective effects in the 3-acetylpyridine (3AP) toxicity model in rats. The purpose of the present
Mahyar Janahmadi et al.
Neurotoxicology, 30(3), 393-402 (2009-05-16)
Riluzole has been shown to possess neuroprotective effects in a variety of neurological and animal model of diseases, including motor diseases. However, the mechanism(s) by which riluzole preserves the intrinsic electrophysiological characteristics of neuronal membrane has not been fully delineated.
S J Moss et al.
Brain research, 920(1-2), 1-9 (2001-11-22)
Data from other laboratories suggest that neurons in the inferior olivary nucleus (IO) may play a role in the modulation of rhythmic tongue movements in rats. Because of its known harmful effects on neurons of the IO, it was suspected
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