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06676

Sigma-Aldrich

Methoxypolyethylene glycol amine

2,000, extent of labeling: ≥0.4 mmol/g NH2 loading

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Synonym(s):
O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine
Linear Formula:
H2NCH2CH2(OCH2CH2)nOCH3
CAS Number:
80506-64-5
MDL number:
MFCD00131599
PubChem Substance ID:
24845957
NACRES:
NA.22

Quality Level

100

form

powder

extent of labeling

≥0.4 mmol/g NH2 loading

InChI

1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3

InChI key

ASUDFOJKTJLAIK-UHFFFAOYSA-N

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1 of 4

This Item
066790796507966
Methoxypolyethylene glycol amine 2,000, extent of labeling: ≥0.4 mmol/g NH2 loading

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06676

Methoxypolyethylene glycol amine

Methoxypolyethylene glycol amine 5,000, extent of labeling: ≥0.17 mmol/g NH2 loading

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06679

Methoxypolyethylene glycol amine

Methoxypolyethylene glycol amine 10,000

Sigma-Aldrich

07965

Methoxypolyethylene glycol amine

Methoxypolyethylene glycol amine 20,000

Sigma-Aldrich

07966

Methoxypolyethylene glycol amine

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

extent of labeling

≥0.4 mmol/g NH2 loading

extent of labeling

≥0.17 mmol/g NH2 loading

extent of labeling

-

extent of labeling

-

Application

Methoxypolyethylene glycol amine (mPEG-NH2) can be used:
  • As a supporting material in the synthesis of polymer-lipid conjugates.
  • As an initiator for ring-opening polymerization (ROP) of N-substituted N-carboxy anhydrides (NNCAs) to prepare polypeptoids.

Other Notes

Soluble polymer support for peptide synthesis; Preparation of various conjugates containing polyethylene glycol; Review

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Schiff base and reductive amination reactions of α-amino acids: a facile route toward N-alkylated amino acids and peptoid synthesis
Fu X, et al.
Polym. Chem., 9(37), 4617-4624 (2018)
Synthesis of Poly (ethylene glycol)-Polydiacetylene Conjugates and Their Micellar and Chromic Characteristics
Choi H et al.
Journal of Nanoscience and Nanotechnology, 8(10), 5104-5108 (2008)
M. Leonard et al.
Tetrahedron, 40, 1581-1581 (1984)
R Colombo et al.
Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 362(10), 1385-1391 (1981-10-01)
The liquid-phase synthesis of two pentapeptides corresponding to the amino acid sequence of Leu- and Met-enkephalin is described. Modified monofunctional poly(ethylene glycol) containing a p-alkoxybenzyl alcohol functional group was employed as the soluble polymeric support. Cleavage of the peptides from
M. Mutter et al.
Reactive Polymers, 6, 99-99 (1987)
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