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07270

Methyl 6-aminohexanoate hydrochloride

≥99.0% (AT)

Synonym(s):

Methyl 6-aminocaproate hydrochloride

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About This Item

Linear Formula:
NH2(CH2)5COOCH3 · HCl
CAS Number:
1926-80-3
Molecular Weight:
181.66
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
329748390
MDL number:
MFCD00035455
Beilstein/REAXYS Number:
3687692
Assay:
≥99.0% (AT)
Form:
powder or crystals

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Product Name

Methyl 6-aminohexanoate hydrochloride, ≥99.0% (AT)

InChI

1S/C7H15NO2.ClH/c1-10-7(9)5-3-2-4-6-8;/h2-6,8H2,1H3;1H

SMILES string

Cl.COC(=O)CCCCCN

InChI key

YSLDOTFAFZJPOC-UHFFFAOYSA-N

assay

≥99.0% (AT)

form

powder or crystals

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

117-124 °C

application(s)

peptide synthesis

Quality Level

200

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This Item
CDS025287733679220515
Methyl 6-aminohexanoate hydrochloride ≥99.0% (AT)

Sigma-Aldrich

07270

Methyl 6-aminohexanoate hydrochloride

6-Amino-2,4-dichloro-3-ethylphenol hydrochloride AldrichCPR

Sigma-Aldrich

CDS025287

6-Amino-2,4-dichloro-3-ethylphenol hydrochloride

6-Amino-1-hexanethiol hydrochloride

Sigma-Aldrich

733679

6-Amino-1-hexanethiol hydrochloride

Methyl benzimidate hydrochloride 97%

Sigma-Aldrich

220515

Methyl benzimidate hydrochloride

assay

≥99.0% (AT)

assay

-

assay

-

assay

97%

form

powder or crystals

form

-

form

solid

form

-

reaction suitability

reaction type: solution phase peptide synthesis

reaction suitability

-

reaction suitability

-

reaction suitability

-

color

white

color

-

color

-

color

-

mp

117-124 °C

mp

-

mp

125-130 °C

mp

105-107 °C (dec.) (lit.)

application(s)

peptide synthesis

application(s)

-

application(s)

-

application(s)

-

Application

Methyl 6-aminohexanoate hydrochloride is used to synthesize papain-catalyzed peptides. [1]

General description

Methyl 6-aminohexanoate hydrochloride also known as Methyl 6-aminocaproate hydrochloride, is commonly used in the solution-phase peptide synthesis.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN1043
BCCM6278
BCCK6254
BCBQ9970V
BCCJ2962

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Papain-catalyzed synthesis of polyglutamate containing a nylon monomer unit
K Yazawa
Polymers, 8, 194-194 (2016)
Petr Chytil et al.
Molecular pharmaceutics, 15(9), 3654-3663 (2018-03-16)
Herein, the biodegradable micelle-forming amphiphilic N-(2-hydroxypropyl) methacrylamide (HPMA)-based polymer conjugates with the anticancer drug doxorubicin (Dox) designed for enhanced tumor accumulation were investigated, and the influence of their stability in the bloodstream on biodistribution, namely, tumor uptake, and in vivo
Tomáš Etrych et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 58, 1-12 (2014-03-19)
In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly bound via a pH-sensitive hydrazone and partly via
Martin Studenovský et al.
Anticancer research, 35(2), 753-757 (2015-02-11)
In the present study, we describe the synthesis and physicochemical properties of a novel pH- and thermoresponsive micellar drug delivery system for an anticancer ellipticinium derivative based on the triblock copolymer poly(ethylene oxide)-block-[tert-butylacrylamide-co-6-(N-methacryloylamino)hexanoic acid hydrazide]-block-poly(ethylene oxide). The system was designed

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