Sudan I is a lysochrome, a diazo-conjugate dye, used as an industrial dye, added to products such as waxes, oils, petrol, solvents and polishes. Sudan I is a category 3 carcinogen previously, now banned, used to color certain foodstuffs.
Journal of chromatography, 435(1), 113-126 (1988-01-01)
The adsorption and partition properties of several fatty acid esters of capsanthin, capsorubin, beta-cryptoxanthin, lutein, violaxanthin and beta-citraurin isolated from fruits were studied by normal-phase (silica) and reversed-phase (octadecylsilane) liquid chromatography using Sudan 1 as internal standard. The separation on
Analytical and bioanalytical chemistry, 401(4), 1411-1422 (2011-07-07)
Sudan dyes have been found to be added to chilli and chilli products for illegal colour enhancement purposes. Due to the possible carcinogenic effect, they are not authorized to be used in food in the European Union or the USA.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48 Suppl 1, S106-S111 (2010-02-02)
Sudan I is generally considered mutagenic based on various in vitro and in vivo tests and is carcinogenic in the rat. Dose-response modelling of the data for hepatocellular adenomas in male rats gave a BMDL(10) of 7.3mg/kg-bw/day. Sudan I is
Chemical research in toxicology, 26(2), 290-299 (2013-01-08)
Sudan I (1-phenylazo-2-hydroxynaphthol) is a suspected human carcinogen causing tumors in the livers and urinary bladders of rats, mice, and rabbits. Here, we investigated for the first time the influence of Sudan I exposure on the expression of several biotransformation
Toxicological sciences : an official journal of the Society of Toxicology, 117(2), 359-374 (2010-07-10)
Free radicals generated during peroxidase-catalyzed oxidation of two xenobiotics, carcinogenic Sudan I and an anticancer agent ellipticine, easily attack unmodified proteins but not glycoproteins. A significant inverse correlation between the extent of glycosylation of proteins and the degree of binding
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.