104094

Sigma-Aldrich

Piperidine

ReagentPlus®, 99%

Synonym(s):
Hexahydropyridine
Empirical Formula (Hill Notation):
C5H11N
CAS Number:
Molecular Weight:
85.15
Beilstein/REAXYS Number:
102438
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.94 (vs air)
3 (vs air)

Quality Level

vapor pressure

23 mmHg ( 20 °C)
23 mmHg ( 20 °C)

product line

ReagentPlus®

assay

99%

impurities

≤0.5% water (Karl Fischer)

refractive index

n20/D 1.452 (lit.)

bp

106 °C (lit.)

mp

−13 °C (lit.)

solubility

organic solvents: soluble(lit.)
water: miscible(lit.)

density

0.862 g/mL at 20 °C (lit.)

SMILES string

C1CCNCC1

InChI

1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2

InChI key

NQRYJNQNLNOLGT-UHFFFAOYSA-N

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General description

Piperidine can be prepared either by nickel catalyzed hydrogenation of pyridine or by cobalt catalyzed hydrogenolysis of tetrahydrofurylamine It forms adducts with α,β,γ,δ-tetraphenylporphyriniron(II) and protoporphyriniron(II). Mossbauer spectra of these adducts have been evaluated. It constitutes the skeleton of various alkaloids. Its chemical reactivity has been discussed.

Application

Piperidine may be employed as protective and structure-directing agent in the post synthesis of MCM (Mobil Composition of Matter)-49 zeolites.

Packaging

5, 100, 4×100, 500 mL in glass bottle
1, 2.5 L in glass bottle

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 2401 3(8) / PGI

WGK Germany

WGK 1

Flash Point(F)

60.8 °F - closed cup

Flash Point(C)

16 °C - closed cup

Certificate of Analysis

Certificate of Origin

Simultaneous recrystallization and post-synthesis of MCM-49 zeolite by TEAOH/piperidine: Implication on the acidity and catalytic alkylation performance.
Shi Y, et al.
Microporous and Mesoporous Materials : The Official Journal of the International Zeolite Association, 220, 7-15 (2016)
Rubiralta M, et al.
Piperidine: Structure, Preparation, Reactivity, and Synthetic Applications of Piperidine and its Derivatives, 43, 14-14 (2013)
Rubiralta M, et al.
Piperidine: Structure, Preparation, Reactivity, and Synthetic Applications of Piperidine and its Derivatives, 43, 3-3 (2013)
Rubiralta M, et al.
Piperidine: Structure, Preparation, Reactivity, and Synthetic Applications of Piperidine and its Derivatives, 43, 2-2 (2013)
Moessbauer spectra of some porphyrin complexes with pyridine, piperidine, and imidazole.
Epstein LM, et al.
Inorganic Chemistry, 6(9), 1720-1724 (1967)
Articles
Amide bonds are ubiquitous in both nature and industrial applications. They are vital to the structure and function of biological macromolecules and polymers. The importance of this functionality has resulted in numerous approaches to its formation, ranging from stoichiometric activation of carboxylic acids to more recent advances in catalytic amide bond formation.
Read More

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