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114529

Sigma-Aldrich

Phenol Red

ACS reagent

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Synonym(s):
Phenolsulfonphthalein
Empirical Formula (Hill Notation):
C19H14O5S
CAS Number:
143-74-8
Molecular Weight:
354.38
Beilstein:
326470
EC Number:
205-609-7
MDL number:
MFCD00003552
PubChem Substance ID:
24847179
NACRES:
NA.47

grade

ACS reagent

Quality Level

200

form

powder

clarity of soln

passes test

technique(s)

titration: suitable

visual transition interval

6.8-8.2, yellow to red

λmax

360 nm
557 nm (2nd)

ε (extinction coefficient)

≥10000 at 288-294 nm in H2O
≥55000 at 555-561 nm in H2O
≥7000 at 357-363 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc(cc1)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)cc4

InChI

1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H

InChI key

BELBBZDIHDAJOR-UHFFFAOYSA-N

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This Item
P4758P0290P3532
Phenol Red ACS reagent

Sigma-Aldrich

114529

Phenol Red

Phenol Red sodium salt

Sigma-Aldrich

P4758

Phenol Red sodium salt

Phenol red solution 0.5%, liquid, sterile-filtered, BioReagent, suitable for cell culture

Sigma-Aldrich

P0290

Phenol red solution

Phenol Red powder, BioReagent, suitable for cell culture

Sigma-Aldrich

P3532

Phenol Red

form

powder

form

powder

form

liquid

form

powder

technique(s)

titration: suitable

technique(s)

titration: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

λmax

360 nm, 557 nm (2nd)

λmax

-

λmax

-

λmax

-

ε (extinction coefficient)

≥10000 at 288-294 nm in H2O, ≥55000 at 555-561 nm in H2O, ≥7000 at 357-363 nm in H2O

ε (extinction coefficient)

-

ε (extinction coefficient)

-

ε (extinction coefficient)

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

diagnostic assay manufacturing

General description

Phenol Red is a phenolsulfonphthalein compound. It is present as a sulfonated hydroxyquinone in weakly acidic aqueous solutions. In alkaline solutions, the dye forms a hydrophilic dianion (a small, red anion that has a larger conjugated system than the yellow hydroxyquinone).

Application

Phenol red is commonly used as a pH indicator in biology and medicine. It is incorporated into microbiological culture media for the identification of Escherichia coli strains. Its clinical diagnostic applications include the investigation of gastric and duodenal ulcers and the assessment of tear function in ophthalmology. Phenol red is also used as a tracer to assess the permeability of the ileal mucosal membrane and to assess bacterial leakage through root-filling materials in dentistry.
Phenol Red has been used for the preparation of phenol red gavage meal for measurement of gastric emptying in rats.
Suitable for use as a pH indicator.

Biochem/physiol Actions

Phenol Red is a pH indicator which changes color from yellow to red.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H335

Hazard Classifications

Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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