124737

Sigma-Aldrich

Glycolic acid

ReagentPlus®, 99%

Synonym(s):
Hydroxyacetic acid
Linear Formula:
HOCH2COOH
CAS Number:
Molecular Weight:
76.05
Beilstein/REAXYS Number:
1209322
EC Number:
MDL number:
eCl@ss:
39021303
PubChem Substance ID:
NACRES:
NA.21

Quality Level

product line

ReagentPlus®

assay

99%

mp

75-80 °C (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

SMILES string

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI key

AEMRFAOFKBGASW-UHFFFAOYSA-N

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General description

Glycolic acid (Hydroxyacetic acid) is an α-hydroxy acid. Glycolic acid solutions having concentration of 70% and pH range of 0.08 to 2.75 are widely employed as superficial chemical peeling agents. Various oligomers or polymers of lactic and/or glycolic acid (low molecular weight) have been prepared. Glycolic acid can be determined via plant tissue coupled flow injection chemiluminescence biosensors, which can be used both as a plant-tissue based biosensor and chemiluminescence flow sensor.

Application

Glycolic acid (Hydroxyacetic acid) has been used in the preparation of PLGA-PEG-PLGA copolymer (PLGA = poly(lactic/glycolic, PEG = polyethylene glycol).

Packaging

25, 100, 500 g in poly bottle
12 kg in poly drum

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 3261 8 / PGII

WGK Germany

WGK 1

Flash Point(F)

572.0 °F - (decomposition)

Flash Point(C)

> 300 °C - (decomposition)

Certificate of Analysis

Certificate of Origin

?Plant Tissue-Based Chemiluminescence Flow Biosensor for Glycolic Acid?
Li B, et al.
Analytical Chemistry, 73(6), 1203-1206 (2001)
Sima Shahabi et al.
TheScientificWorldJournal, 2014, 420616-420616 (2015-01-13)
Gamma irradiation is able to affect various structural and biological properties of biomaterials In this study, a composite of Hap/PLGA-PEG and their ingredients were submitted to gamma irradiation doses of 25 and 50 KGy. Various properties such as molecular weight (GPC)...
"A novel renewable plant tissue-based electrochemiluminescent biosensor for glycolic acid"
Zhu L, et al.
Sensors and Actuators B, Chemical, 98(2), 115-121 (2004)
F F Becker et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 22(5), 463-465 (1996-05-01)
Seventy percent glycolic acid solutions are being commonly used as superficial chemical peeling agents. The pH of these solutions ranges from 0.08 to 2.75. The histologic effects of these various pH solutions on human skin have not been studied. The...
N Wang et al.
Journal of biomaterials science. Polymer edition, 8(12), 905-917 (1997-01-01)
A series of oligomers or low molecular weight polymers of lactic and/or glycolic acid has been synthesized with different molar ratios of lactic to glycolic acid. These oligomers have been characterized with respect to oligomer composition, molecular weight, intrinsic viscosity...

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