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131105

Sigma-Aldrich

3,6-Diaminoacridine hydrochloride

Dye content 95 %

Synonym(s):

Proflavine hydrochloride, Proflavine monohydrochloride

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$427.00

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5 G
$90.20
25 G
$427.00

About This Item

Empirical Formula (Hill Notation):
C13H11N3 · HCl
CAS Number:
952-23-8
Molecular Weight:
245.71
EC Number:
213-459-9
MDL number:
MFCD00066867
UNSPSC Code:
12171500
PubChem Substance ID:
24847995
NACRES:
NA.47

$90.20

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assay

94.0% (HPLC)

form

powder

composition

Dye content, 95%

mp

270 °C (dec.) (lit.)

solubility

H2O: 1 mg/mL, clear

λmax

456 nm

ε (extinction coefficient)

50000 at 260 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1

InChI

1S/C13H11N3.ClH/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h1-7H,14-15H2;1H

InChI key

PBBGTVBGXBUVLT-UHFFFAOYSA-N

Related Categories

Application

3, 6-Diaminoacridine hydrochloride has been used for studying cation transfer at the liquid–liquid interface.[1]
An intercalating dye.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
16806CB
05405KZ
09203PG
01508CF
U16635

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Amino-isocyanoacridines (ICAAcs), as first members of their class, turned out to be a novel, multifunctional acridine orange (AO) type dye family with a number of additional favorable properties. They have enhanced solvatochromic emission range, low quantum yields (ΦF = 2.9-0.4%) in water
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The binding of proflavine, an acriflavine derivative, with the RNA polynucletodide polyadenylic acid-polyuridylic acid is investigated here to understand the structural and thermodynamic basis of the binding process. Such binding data are crucial for designing viable theraperutic agents. Spectroscopic studies
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Nanomaterials (Basel, Switzerland), 10(5) (2020-05-14)
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Journal of photochemistry and photobiology. B, Biology, 165, 42-50 (2016-10-22)
Interaction of proflavine with hemoglobin (Hgb) was studied employing spectroscopy, calorimetry, and atomic force microscopy. The equilibrium constant was found to be of the order 10
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